Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

2.9K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
2.9K
Clearance Models: Physiological Models01:09

Clearance Models: Physiological Models

328
Drug clearance is a critical pharmacokinetic process involving the irreversible removal of drugs from the body through various organs over a specified time period. Physiological models are indispensable in determining organ-specific clearance, defined by the proportion of the drug eliminated per unit of time from the organ's blood volume.
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's...
328
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

788
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
788
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

616
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
616
Self-Help Support Groups01:28

Self-Help Support Groups

363
Self-help support groups are voluntary, community-based organizations that provide a platform for individuals with shared concerns to exchange support, insights, and practical strategies for coping with life challenges. Typically led by group members or paraprofessionals, these groups form a cornerstone of mental health care, especially in reaching populations that are underserved by traditional healthcare systems.
Accessibility and Cost-Effectiveness
One of the primary strengths of self-help...
363
Decision Making01:20

Decision Making

1.0K
Decision-making is a fundamental cognitive process that involves evaluating alternatives and selecting among them. This process can range from simple choices, such as deciding what to wear, to complex decisions, like choosing a major in college or a career path. The complexity of the decision often dictates the approach we use, which can be broadly categorized into two types: automatic and controlled decision-making.
Automatic decision-making is fast, intuitive, and relies on gut feelings...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated comprehensive assessment for predicting weaning success in difficult-to-wean critically ill patients: the WEAN-US study.

Critical care (London, England)·2026
Same author

Identification of physiological clusters in acute hypoxemic respiratory failure patients undergoing non-invasive respiratory support using EIT-based t-SNE and spectral clustering.

Intensive care medicine experimental·2026
Same author

A consensus roadmap for post-traumatic epilepsy: Clinical biomarkers, research priorities, policy barriers, and pathways to interventional trials.

Epilepsia·2026
Same author

Does Hypotension Prediction Index limit the occurrence of postoperative complications associated with intraoperative hypotension? A systematic review and model-averaged Bayesian meta-analysis of statistically sound studies.

Journal of anesthesia·2026
Same author

Heparinised saline versus normal saline flushing in maintaining arterial catheter patency in intensive care patients: A systematic review and meta-analysis of randomised controlled trials.

Australian critical care : official journal of the Confederation of Australian Critical Care Nurses·2026
Same author

Targeting PRMTs Creates Vulnerability of DNA Double-Stand Break Repair Pathways, and Potentiates Chemotherapy Efficacy in TNBC.

Cancer science·2026
Same journal

The authors reply.

Critical care medicine·2026
Same journal

Attracting Emergency Medicine Graduates to Surgical Critical Care Training Programs.

Critical care medicine·2026
Same journal

The authors reply.

Critical care medicine·2026
Same journal

Beyond a Snapshot: Tracking Family Prognostic Expectations in the ICU.

Critical care medicine·2026
Same journal

The authors reply.

Critical care medicine·2026
Same journal

Plasma Levels of Soluble ST2 Reflect Extrapulmonary Organ Dysfunction and Predict Outcomes in Acute Respiratory Failure: Beware of Potential Confounders.

Critical care medicine·2026
See all related articles

Related Experiment Video

Updated: Feb 12, 2026

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents
06:57

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents

Published on: July 9, 2020

6.6K

An Open-Loop, Physiologic Model-Based Decision Support System Can Provide Appropriate Ventilator Settings.

Dan Stieper Karbing1, Savino Spadaro2, Nilanjan Dey3

  • 1Respiratory and Critical Care Group, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.

Critical Care Medicine
|April 10, 2018
PubMed
Summary
This summary is machine-generated.

A clinical decision support system safely reduced mechanical ventilation settings in ICU patients. The system provided appropriate advice, leading to significant decreases in ventilation and potentially aiding in extubation.

More Related Videos

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

1.6K
A Community-based Stress Management Program: Using Wearable Devices to Assess Whole Body Physiological Responses in Non-laboratory Settings
10:45

A Community-based Stress Management Program: Using Wearable Devices to Assess Whole Body Physiological Responses in Non-laboratory Settings

Published on: January 22, 2018

8.1K

Related Experiment Videos

Last Updated: Feb 12, 2026

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents
06:57

Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents

Published on: July 9, 2020

6.6K
Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

1.6K
A Community-based Stress Management Program: Using Wearable Devices to Assess Whole Body Physiological Responses in Non-laboratory Settings
10:45

A Community-based Stress Management Program: Using Wearable Devices to Assess Whole Body Physiological Responses in Non-laboratory Settings

Published on: January 22, 2018

8.1K

Area of Science:

  • Critical Care Medicine
  • Biomedical Engineering
  • Respiratory Physiology

Background:

  • Mechanical ventilation is a critical intervention in intensive care units (ICUs).
  • Optimizing ventilation settings is essential for patient outcomes and reducing complications.
  • Clinical decision support systems (CDSS) offer potential for improving mechanical ventilation management.

Purpose of the Study:

  • To evaluate the physiological effects of implementing a physiologic model-based CDSS for mechanical ventilation.
  • To assess the impact of CDSS-guided ventilation adjustments on patient respiratory parameters.

Main Methods:

  • A prospective, observational study was conducted in university and regional hospital ICUs.
  • Seventy-two adult ICU patients on mechanical ventilation were included.
  • Physicians accepted and applied CDSS advice for 4-8 hours, with high adherence (95.7%).

Main Results:

  • In pressure support ventilation, advice led to significant pressure support reduction, facilitating extubation in 37% of patients.
  • In control mode ventilation, settings were significantly decreased, with tidal volume reduced below 8 mL/kg predicted body weight in 29% of patients.
  • Fraction of end-tidal CO2 and respiratory rate/tidal volume remained within acceptable limits, and fraction of inspired oxygen was reduced.

Conclusions:

  • The CDSS provided appropriate mechanical ventilation suggestions in a diverse ICU population.
  • The system effectively reduced ventilation settings to potentially safe and beneficial levels.
  • This technology shows promise for optimizing mechanical ventilation management in critical care settings.