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Lyme disease. A neuro-ophthalmologic view
1Department of Pathology, Southampton Hospital, NY 11968.
Journal of Clinical Neuro-Ophthalmology
|December 1, 1987
Summary
Lyme borreliosis, a complex spirochetal infection, presents diverse symptoms, particularly affecting neuro-ophthalmology. This review covers diagnosis challenges, like false-negative serology, and treatment options for Lyme disease.
Area of Science:
- Infectious Diseases
- Neurology
- Ophthalmology
Background:
- Lyme borreliosis is a tick-borne spirochetal illness caused by Borrelia burgdorferi.
- It exhibits a wide range of clinical manifestations, similar to syphilis.
- Neuro-ophthalmologic involvement is a significant, though often overlooked, aspect of the disease.
Purpose of the Study:
- To review the neuro-ophthalmologic manifestations of Lyme borreliosis.
- To provide a historical overview of Lyme disease.
- To discuss diagnostic challenges and therapeutic strategies.
Main Methods:
- Literature review focusing on Lyme borreliosis.
- Emphasis on neuro-ophthalmologic presentations.
- Discussion of diagnostic pitfalls and treatment.
Main Results:
- Lyme borreliosis can present with varied and complex symptoms.
- False-negative serology is a common diagnostic pitfall.
- Effective therapeutic options are available.
Conclusions:
- Neuro-ophthalmologic findings are crucial in diagnosing Lyme borreliosis.
- Accurate diagnosis requires awareness of potential pitfalls, especially serology.
- Timely and appropriate treatment is essential for managing Lyme disease.