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Updated: Aug 14, 2026
An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
Photodynamic therapy
M J Manyak1, A Russo, P D Smith
1National Cancer Institute, Radiation Oncology Branch, Bethesda, MD 20892.
Abstract:
Photodynamic therapy (PDT) is an experimental cancer treatment modality that selectively destroys cancer cells by an interaction between absorbed light and a retained photosensitizing agent. This review discusses the basic components of photodynamic activity and examines the clinical applications of photodynamic therapy in cancer treatment. Treatment of superficial and early-stage malignancies is encouraging. Technologic advancement and further elucidation of the fundamental basis of photodynamic action should permit treatment of more advanced malignancies.
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