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Updated: Dec 24, 2025

Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis
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Prostatic Urethral Lift: Does Size Matter?

Bhavik B Shah1, Kevin Tayon2, SriGita Madiraju2

  • 11 Department of Urology, Morsani College of Medicine, University of South Florida , Tampa, Florida.

Journal of Endourology
|April 11, 2018
PubMed
Summary
This summary is machine-generated.

Prostatic urethral lift (PUL) effectively treats benign prostatic hypertrophy (BPH) in larger prostates (>80g). This minimally invasive procedure shows significant symptom improvement, comparable to smaller prostates, with no difference in outcomes.

Keywords:
Uroliftbenign prostatic hypertrophyejaculatory functionlarge prostateprostatic liftretention

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Area of Science:

  • Urology
  • Minimally Invasive Surgery
  • Benign Prostatic Hyperplasia (BPH) Management

Background:

  • Prostatic urethral lift (PUL) is an endoscopic treatment for BPH, retracting tissue to relieve obstruction.
  • Current guidelines restrict PUL to prostates <80g, based on the L.I.F.T. study.
  • The efficacy of PUL in larger prostates remains under investigation.

Purpose of the Study:

  • To evaluate the effectiveness of PUL in patients with benign prostatic hyperplasia (BPH) and larger prostate volumes (>80g).
  • To compare outcomes of PUL in patients with prostates <80g versus >80g.

Main Methods:

  • Retrospective analysis of 74 patients undergoing PUL for BPH.
  • Patients were divided into two groups: <80g (n=51) and >80g (n=23) prostate size.
  • Statistical comparison using Student t-tests and Fisher's exact tests.

Main Results:

  • Both <80g and >80g groups showed significant improvement in AUA symptom scores post-PUL.
  • No significant differences were observed in age, pre- or post-procedure AUA symptom scores, or need for additional procedures between groups.
  • Patients with larger prostates (>80g) were more likely to have a median lobe requiring resection.

Conclusions:

  • Prostatic urethral lift (PUL) demonstrates effectiveness in managing BPH symptoms for patients with larger prostates (>80g).
  • Consideration of median lobe resection during PUL may benefit patients with larger prostates.
  • Further long-term studies are necessary to confirm the durability of PUL in this patient cohort.