Successful pulmonary arterial embolization followed by curative surgery for a lepidic predominant lung adenocarcinoma with severe hypoxemia
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Updated: Feb 12, 2026

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
Published on: October 25, 2024
Louise Sebane1, Mostafa El-Hajjam2, Philippe Puyo3
1Department of Respiratory Diseases and Thoracic Oncology, APHP - Ambroise Pare Hospital, 9 Avenue Charles de Gaulle, 92100, Boulogne-Billancourt, France.
Background:
Lepidic predominant adenocarcinoma is characterized by frequent refractory hypoxemia due to intrapulmonary shunting. Severe hypoxemia can induce perioperative complications in case of thoracic surgery.
Case Presentation:
We report a case of a 67 year-old woman with localized lepidic adenocarcinoma in the right lower lobe with severe hypoxemia. A selective arterial lung embolization allowed an instantaneous correction of the hypoxemia, and a curative lobectomy was safely performed 1 week after without any complication. The staging was pT3N0M0, and the patient received adjuvant chemotherapy.
Conclusions:
This is the first case-report of successful endovascular embolization before curative surgery for a lepidic predominant lung adenocarcinoma.
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