Related Experiment Video
Updated: Feb 12, 2026
05:34
A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
Published on: July 18, 2025
556
Mid-term outcomes after biologic mesh use: Does their performance meet our expectations?
P Brinas1, M Chalret du Rieu1, G Tuyeras1
1Chirurgie générale et digestive, hôpital Purpan, CHU de Toulouse, place du Docteur-Baylac, 31059 Toulouse cedex 9, France.
Journal of Visceral Surgery
|April 11, 2018
Summary
Biological prostheses for hernia repair show high rates of recurrence and infection, questioning their clinical utility. Further comparison with semi-absorbable prostheses is needed to evaluate their effectiveness in abdominal wall reconstruction.
Area of Science:
- Surgical innovation
- Biomaterials in medicine
- Hernia repair techniques
Background:
- Biological mesh prostheses are costly and their use is limited, primarily for contaminated parietal repairs.
- Recent studies have questioned the efficacy of biological prostheses.
- This study evaluates outcomes of biological prosthesis use, focusing on hernia recurrence and infectious complications.
Purpose of the Study:
- To assess the efficacy of biological prostheses in hernia repair.
- To investigate rates of hernia recurrence and infectious complications following biological prosthesis implantation.
- To identify risk factors associated with recurrence.
Main Methods:
- Retrospective review of 68 patients who received biological prostheses between 2009 and 2015.
- Analysis of implantation sites (anterior abdominal wall, pelvis).
- Evaluation of early and medium-term post-operative outcomes, including complications and recurrence.
Main Results:
- High incidence of complications: 32.3% early wall abscess, 73% medium-term complications.
- Significant medium-term recurrence rate: 57% developed recurrent herniation.
- Risk factors for recurrence included parastomal hernia and prior hernia recurrence.
Conclusions:
- Biological prostheses are associated with a high rate of medium-term incisional hernia recurrence.
- The findings challenge the current use of biological prostheses in hernia repair.
- Comparative studies with semi-absorbable prostheses are warranted.
Related Concept Videos
01:15Expected Value
7.8K
The expected value is known as the "long-term" average or mean. This means that over the long term of experimenting over and over, you would expect this average. The expected average is represented by the symbol μ. It is calculated as follows:
7.8K
01:20Mesh Analysis
1.5K
Mesh analysis is a valuable method for simplifying circuit analysis using mesh currents as key circuit variables. Unlike nodal analysis, which focuses on determining unknown voltages, mesh analysis applies Kirchhoff's voltage law (KVL) to find unknown currents within a circuit. This method is particularly convenient in reducing the number of simultaneous equations that need to be solved.
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
1.5K
01:08Determination of Expected Frequency
2.6K
Suppose one wants to test independence between the two variables of a contingency table. The values in the table constitute the observed frequencies of the dataset. But how does one determine the expected frequency of the dataset? One of the important assumptions is that the two variables are independent, which means the variables do not influence each other. For independent variables, the statistical probability of any event involving both variables is calculated by multiplying the individual...
2.6K
02:59Biological Effects of Radiation
18.1K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
18.1K
02:24Predicting Reaction Outcomes
11.0K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
11.0K
01:10Mesh Analysis with Current Sources
2.0K
Mesh analysis becomes simpler when analyzing circuits with current sources, whether independent or dependent. The presence of current sources reduces the number of equations required for analysis. Two cases illustrate this:
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
2.0K