Functional Assessment for Acute Stroke Trials: Properties, Analysis, and Application
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Updated: Feb 12, 2026

Computerized Adaptive Testing System of Functional Assessment of Stroke
Published on: January 7, 2019
Martin Taylor-Rowan1, Alastair Wilson1, Jesse Dawson1
1Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Abstract:
A measure of treatment effect is needed to assess the utility of any novel intervention in acute stroke. For a potentially disabling condition such as stroke, outcomes of interest should include some measure of functional recovery. There are many functional outcome assessments that can be used after stroke. In this narrative review, we discuss exemplars of assessments that describe impairment, activity, participation, and quality of life. We will consider the psychometric properties of assessment scales in the context of stroke trials, focusing on validity, reliability, responsiveness, and feasibility. We will consider approaches to the analysis of functional outcome measures, including novel statistical approaches. Finally, we will discuss how advances in audiovisual and information technology could further improve outcome assessment in trials.
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