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Updated: Feb 12, 2026

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
[Organ assist devices in the future : Limits and perspectives]
R Riessen1, U Janssens2, S John3
1Internistische Intensivstation, Department für Innere Medizin, Universitätsklinikum Tübingen, Otfried-Müller-Str. 10, 72076, Tübingen, Deutschland. reimer.riessen@med.uni-tuebingen.de.
Extracorporeal membrane oxygenation (ECMO) is increasingly used for severe organ failure, but patient selection remains challenging. Centralizing ECMO in specialized centers and conducting further research are crucial for optimizing outcomes.
Area of Science:
- Critical Care Medicine
- Cardiovascular Surgery
- Respiratory Medicine
Background:
- Extracorporeal organ assist devices, including extracorporeal membrane oxygenation (ECMO), are increasingly utilized for severe respiratory failure and cardiogenic shock.
- Despite technical advancements, ECMO carries significant risks and the scientific evidence supporting its use is still limited.
Purpose of the Study:
- To highlight the challenges in selecting patients who will benefit most from ECMO.
- To emphasize the need for comprehensive patient evaluation, including underlying disease, comorbidities, and functional status, within an interdisciplinary team.
- To address the ethical considerations associated with ECMO therapy.
Main Methods:
- Review of current practices and challenges in ECMO patient selection.
- Emphasis on interdisciplinary team approach for comprehensive patient assessment.
- Discussion of organizational demands and ethical considerations.
Main Results:
- Patient selection for ECMO remains a significant challenge for intensivists and medical teams.
- Thorough evaluation of disease etiology, comorbidities, and patient's functional status is essential.
- Ethical challenges are inherent in complex ECMO treatments.
Conclusions:
- ECMO treatment requires careful patient selection and a multidisciplinary approach.
- Concentrating ECMO treatments in specialized, qualified centers is recommended due to complexity and organizational demands.
- Further comprehensive scientific analysis of ECMO treatment data is essential to improve patient outcomes.
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