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Updated: Feb 12, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Spontaneous formation and closure of full thickness macular hole in a vitrecto-mised eye : a case report
Abstract:
The exact pathogenesis of macular hole (MH) is controversial with most of the cases being idiopathic. Trauma is an important cause of secondary MH formation. MH post Pars Plana Vitrectomy (PPV) is an even rare entity with only a handful of cases reported so far ( Kumagai et al, 2008; Smiddy W.E, 1993; Kimura et al, 2005). An even rarer event is spontaneous closure of post PPV full thickness macular hole (FTMH), though spontaneous closure of traumatic macular hole (TMH) has been reported before. Herein, we report a 26 year old male patient who developed FTMH post PPV that closed spontaneously.
Insights
A rare case of spontaneous closure of a full-thickness macular hole (FTMH) after pars plana vitrectomy (PPV) is presented. This finding offers new insights into macular hole pathogenesis and potential natural healing mechanisms.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Macular holes (MH) pathogenesis is often idiopathic, though trauma can cause secondary MH.
- Macular holes following pars plana vitrectomy (PPV) are rare, with few documented cases.
- Spontaneous closure of traumatic MH is known, but rare for post-PPV FTMH.
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