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Updated: Feb 12, 2026
08:47
The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
Published on: November 19, 2008
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Cutaneous complication of perinatal hypoxia
1Dermatology Department, Hospital de Santarém EPE, Santarém, Portugal. margaridagaiorato@gmail.com.
Dermatology Online Journal
|April 11, 2018
Summary
Subcutaneous fat necrosis of the newborn is a rare condition that typically resolves on its own. Close monitoring for complications like hypercalcemia is crucial for affected infants.
Area of Science:
- Neonatology
- Dermatology
- Pediatrics
Background:
- Subcutaneous fat necrosis of the newborn (SCFN) is a rare panniculitis affecting newborns.
- It typically occurs in term infants with perinatal complications.
Observation:
- A case of a term neonate with hypoxic-ischemic encephalopathy presented with seizures.
- Erythematous nodules and plaques developed on the infant's arm and back nine days after birth.
- Skin biopsy confirmed subcutaneous fat necrosis of the newborn.
Findings:
- While generally self-healing, SCFN can lead to serious complications.
- Potential complications include thrombocytopenia, hypoglycemia, hypertriglyceridemia, and hypercalcemia.
- Serum calcium levels were normal in this patient initially.
Implications:
- Regular monitoring of serum calcium is essential for up to six months.
- Early diagnosis and treatment of hypercalcemia are critical to prevent severe outcomes.
- This case highlights the importance of recognizing SCFN and its potential complications, even in neonates without typical perinatal issues.
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