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Updated: Feb 12, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
Capillary hemangioma associated with dermal atrophy masquerading as a deep fungal infection
Jennifer L Strunck1, Scott R Florell, Douglas Grossman
1Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah.
Abstract:
Hemangiomas are benign vascular neoplasms which arise in early adulthood. Herein we present a 79-year-old woman with a hemangioma of the lower flank masquerading as a cutaneous manifestation of a systemic fungal infection upon initial histological analysis. Decreased elastin and collagen within the lesion likely accounted for the clumping and splaying of the capillaries into "hyphae-like" structures. Loss of dermal elastic tissue and collagen apparently concentrated the capillary proliferation into an unusual morphology mimicking the hyphal structures. Through additional staining methods the lesion was confirmed to be an unusual presentation of a capillary hemangioma.
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