Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Communication01:03

Communication

8.8K
Communication between two animals occurs when one animal transmits an information signal that causes a change in the animal that receives the information. Organisms communicate with one another in a host of different ways. Signals can be auditory, chemical, visual, tactile, or a combination of these. Communication is a critical behavioral adaptation that promotes survival, growth, and reproduction.
8.8K
Communication01:28

Communication

11.5K
Sharing information, concepts, and emotions to foster mutual understanding is communication. The sender, recipient, and transaction must be considered in this manner. The sender is the person who shares the message, the recipient is the person who receives and understands the message, and the transaction is the method used to deliver the message and the variables that affect the communication's context and surroundings. The nurse-client connection is built on therapeutic communication.
11.5K
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

1.3K
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
1.3K
CNS Depressants: Barbiturates and Benzodiazepines01:14

CNS Depressants: Barbiturates and Benzodiazepines

1.4K
CNS depressants include drugs from the category of barbiturates and benzodiazepines. They are valuable medications for managing anxiety disorders and insomnia. Barbiturates, once used to induce and maintain sleep, have been replaced mainly by benzodiazepines due to barbiturate's toxicity, tolerance, and overdose risks. They interact with GABAA receptors, leading to sedation at low doses and potentially coma and death at higher doses. Phenobarbital, a long-acting barbiturate, possesses...
1.4K
Neuronal Communication01:28

Neuronal Communication

3.5K
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
3.5K
Therapeutic Communication01:30

Therapeutic Communication

8.6K
Communication is a lifelong learning process. Through therapeutic communication, nurses can collect relevant assessment data, provide education and counseling, and interact during nursing interventions. Sending and receiving messages occur through verbal and nonverbal communication techniques and can happen separately or simultaneously.
Verbal communication depends on language or a prescribed way of using words so that people can share information effectively. The critical aspects of verbal...
8.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retinal ganglion cell survival and functional maturation in transiently vascularized human retinal organoids.

Cell stem cell·2026
Same author

Enhancing Tyro3 signaling ameliorates IL-1β production through STAT1 in Alzheimer's disease models.

Journal of leukocyte biology·2025
Same author

Neurovascular dynamics in the spinal cord from development to pathophysiology.

Neuron·2025
Same author

Modulation of fibronectin extracellular matrix enhances anti-tumor efficacy of immune checkpoint blockade.

Cell reports. Medicine·2025
Same author

Ablation of hypothalamic Cnr1 leads to reduced meniscal mineral volume and articular cartilage damage in aging male mice.

Osteoarthritis and cartilage·2025
Same author

BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue.

The EMBO journal·2025

Related Experiment Video

Updated: Feb 12, 2026

Dissection of Larval CNS in Drosophila Melanogaster
06:29

Dissection of Larval CNS in Drosophila Melanogaster

Published on: November 9, 2006

20.6K

Neurovascular Communication during CNS Development.

Isidora Paredes1, Patricia Himmels1, Carmen Ruiz de Almodóvar1

  • 1Biochemistry Center, Heidelberg University, 69120 Heidelberg, Germany; Interdisciplinary Center for Neurosciences, Heidelberg University, 69120 Heidelberg, Germany.

Developmental Cell
|April 11, 2018
PubMed
Summary
This summary is machine-generated.

Neural and vascular systems communicate precisely for central nervous system (CNS) development. This review highlights how blood vessels actively shape neural processes, revealing bidirectional communication mechanisms.

Keywords:
CNS developmentCNS vascularizationangiocrine cuebrainneurodevelopmentneurovascular communicationneurovascular linkretinaspinal cordvascular control of neuronal development and function

More Related Videos

Single-cell Microinjection for Cell Communication Analysis
09:59

Single-cell Microinjection for Cell Communication Analysis

Published on: February 26, 2017

11.8K
Assessment of Vascular Regeneration in the CNS Using the Mouse Retina
07:32

Assessment of Vascular Regeneration in the CNS Using the Mouse Retina

Published on: June 23, 2014

14.9K

Related Experiment Videos

Last Updated: Feb 12, 2026

Dissection of Larval CNS in Drosophila Melanogaster
06:29

Dissection of Larval CNS in Drosophila Melanogaster

Published on: November 9, 2006

20.6K
Single-cell Microinjection for Cell Communication Analysis
09:59

Single-cell Microinjection for Cell Communication Analysis

Published on: February 26, 2017

11.8K
Assessment of Vascular Regeneration in the CNS Using the Mouse Retina
07:32

Assessment of Vascular Regeneration in the CNS Using the Mouse Retina

Published on: June 23, 2014

14.9K

Area of Science:

  • Neuroscience
  • Vascular Biology
  • Developmental Biology

Background:

  • Precise communication between the nervous and vascular systems is essential for central nervous system (CNS) formation and function.
  • Traditionally, neural cells were known to regulate vasculature; however, emerging research indicates blood vessels actively influence neurodevelopmental processes.
  • This bidirectional communication is critical for understanding CNS development.

Purpose of the Study:

  • To review current knowledge on how neurons influence blood vessel growth during CNS development.
  • To summarize how blood vessels actively participate in shaping the neural compartment.
  • To discuss the identified molecular mechanisms underlying this neurovascular communication.

Main Methods:

  • Literature review of recent studies on neurovascular interactions in CNS development.
  • Analysis of research focusing on neuronal regulation of vasculature.
  • Examination of studies investigating vascular influence on neural development.

Main Results:

  • Neurons exert influence on growing blood vessels within the CNS.
  • Blood vessels play an active role in shaping neural structures.
  • Specific molecular pathways mediating this bidirectional communication have been identified.

Conclusions:

  • The communication between the nervous and vascular systems is a dynamic, bidirectional process crucial for CNS development.
  • Understanding these interactions and their molecular underpinnings is vital for addressing neurodevelopmental disorders.
  • Future research should continue to elucidate the complex interplay between neurons and vasculature.