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Updated: Feb 12, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Anterior segment optical coherence tomography.

Marcus Ang1, Mani Baskaran2, René M Werkmeister3

  • 1Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore; Moorfields Eye Hospital, London, United Kingdom.

Progress in Retinal and Eye Research
|April 11, 2018
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography (OCT) advances enable detailed, in vivo imaging of the anterior eye segment. This review covers OCT

Keywords:
AngiographyAnterior segmentCorneaGlaucomaOptical coherence tomography

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Area of Science:

  • Ophthalmology
  • Biomedical Imaging
  • Medical Technology

Background:

  • Optical coherence tomography (OCT) is crucial for non-contact, in vivo imaging of ocular structures.
  • Anterior segment OCT (AS-OCT) has evolved significantly, enhancing clinical practice with improved speed and resolution.
  • AS-OCT applications are expanding across various ocular structures and conditions.

Purpose of the Study:

  • To review the historical development of anterior segment OCT.
  • To update on current research and clinical applications of AS-OCT.
  • To highlight technological advancements and future directions in AS-OCT.

Main Methods:

  • Review of historical development and technological advancements in anterior segment OCT.
  • Summary of current research and clinical applications across ocular surface, cornea, anterior chamber, aqueous outflow, and vessels.
  • Discussion of software and image processing improvements.

Main Results:

  • AS-OCT technology has progressed, offering higher resolution and faster imaging speeds.
  • Key applications include dry eye evaluation, intra-operative surgical guidance, and glaucoma assessment.
  • Advancements improve visualization of tear film, surgical procedures, and aqueous humor dynamics.

Conclusions:

  • Anterior segment OCT is a vital tool in ophthalmology, with ongoing technological improvements.
  • Future developments promise enhanced vascular imaging, ultra-high resolution, and 3D reconstruction.
  • Improved image processing enhances clinical utility and interpretation of AS-OCT data.