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Mental load during cognitive performance in complex regional pain syndrome I
M Breimhorst1,2, C Dellen1, M Wittayer1
1Department of Neurology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
European Journal of Pain (London, England)
|April 11, 2018
Summary
High mental load intensifies pain in complex regional pain syndrome (CRPS). This effect is exacerbated by anxiety and depression, highlighting the impact of negative emotional states during stressful cognitive tasks for CRPS patients.
Area of Science:
- Neuroscience
- Psychology
- Pain Management
Background:
- Complex regional pain syndrome (CRPS) is linked to impaired limb recognition.
- Understanding factors influencing pain perception in CRPS is crucial for effective management.
Purpose of the Study:
- To investigate the impact of varying mental load on performance, sympathetic nervous system activity, and pain in CRPS patients.
- To determine if cognitive demands affect pain experience in individuals with CRPS.
Main Methods:
- Twenty CRPS-I patients and twenty healthy controls performed a limb recognition task with manipulated mental load (2s to 10s presentation time).
- Skin conductance was continuously monitored, and pain intensity was assessed before and after task runs.
- State anxiety and depressive symptoms were also evaluated.
Main Results:
- CRPS patients showed no significant differences in limb recognition or skin conductance compared to controls.
- Patients with CRPS reported increased pain during the task, especially under high mental load and later in the task.
- Higher pain intensity during high mental load correlated with state anxiety and depressive symptoms.
Conclusions:
- Elevated mental load exacerbates pain in complex regional pain syndrome (CRPS).
- Negative affective states, such as anxiety and depression, worsen pain perception under high cognitive demand in CRPS.
- Clinical assessments and interventions for CRPS should account for the influence of mental load and psychological factors.
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