Related Experiment Video
Updated: Feb 12, 2026

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Published on: January 31, 2020
Antigen processing and presentation in HIV infection
Julie Boucau1, Sylvie Le Gall1
1Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 02139, United States.
Abstract:
The presentation of virus-derived peptides by MHC molecules constitutes the earliest signals for immune recognition by T cells. In HIV infection, immune responses elicited during infection do not enable to clear infection and correlates of immune protection are not well defined. Here we review features of antigen processing and presentation specific to HIV, analyze how HIV has adapted to the antigen processing machinery and discuss how advances in biochemical and computational protein degradation analyses and in immunopeptidome definition may help identify targets for efficient immune clearance and vaccine immunogen design.
More Related Videos
06:57Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells
Published on: September 18, 2016
13:58Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
Published on: September 26, 2011
Related Concept Videos
Processes of Self-Presentation
Antigen Processing Pathways
MHC Class I: Presenting Endogenous...
Self-Presentation: Self-Monitoring and Self-Handicapping
Self-Presentation
Strategies of Self-Presentation I: Strategic Self-Presentation
Strategies of Self-Presentation II: Self-Verification