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Updated: Feb 12, 2026

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
Published on: April 13, 2021
Fever in a transplant recipient: think beyond infection
Mayanka Kamboj1, Volodymyr Chornyy1, Abhilash Koratala1
1Division of Nephrology, Hypertension and Renal Transplantation University of Florida Gainesville Florida.
Abstract:
Immune reconstitution inflammatory syndrome (IRIS) is an exaggerated inflammatory cascade initiated in response to immune recovery during the resolution of an infection. Reduction in calcineurin inhibitor levels in organ transplant recipients due to enhanced metabolism from interaction with rifampin can predispose these individuals to develop IRIS during the treatment of tuberculosis and mimic sepsis.
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