Related Experiment Video
Updated: Feb 12, 2026

09:15
Measuring Pressure Volume Loops in the Mouse
Published on: May 2, 2016
17.0K
Observational study of laryngoscopy plus flow-volume loops during exercise
Paolo T Pianosi1, Diana M Orbelo2, Shelagh A Cofer2
1Department of Pediatric & Adolescent Medicine Mayo Clinic 200 First St. SW Rochester Minnesota 55905.
Clinical Case Reports
|April 12, 2018
Summary
Diagnosing exercise-induced laryngeal obstruction is best done with laryngoscopy. Combining this with flow-volume loop analysis reveals that cigar-shaped loops indicate obstruction, aiding diagnosis.
Area of Science:
- Exercise physiology
- Respiratory medicine
- Laryngology
Background:
- Exercise-induced laryngeal obstruction (EILO) diagnosis relies on laryngoscopy.
- Inspiratory flow-volume loops (IFVLs) may suggest EILO but lack specificity.
Observation:
- This study integrated tidal IFVL analysis with laryngoscopy during exercise.
- The aim was to identify specific IFVL patterns indicative of EILO.
Findings:
- Cigar-shaped inspiratory loops, not flattened ones, were significantly associated with EILO.
- This specific IFVL morphology correlates with dynamic vocal fold adduction during exercise.
Implications:
- Tidal IFVL analysis can serve as a non-invasive screening tool for EILO.
- Findings may refine diagnostic protocols and inform therapeutic strategies like pursed-lip breathing.
Related Concept Videos
Observational Studies
11.1K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
11.1K
Naturalistic Observations
17.5K
If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
17.5K
Exercise Stress Test
1.4K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
1.4K
Feedback Loops
64.7K
In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
64.7K
Exercise and Muscle Performance
2.5K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
2.5K
Exercise and Cardiac Output
2.0K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
2.0K

