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Recent trends in bioinks for 3D printing.

Janarthanan Gopinathan1,2, Insup Noh1,2

  • 11Department of Chemical & Biomolecular Engineering, Seoul National University of Science and Technology (Seoul Tech), Gongneung-ro 232, Nowon-Gu, Seoul, 01811 Republic of Korea.

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|April 12, 2018
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Summary
This summary is machine-generated.

Advancements in 3D bioprinting utilize novel bioinks for organ regeneration. This review details polymer-based bioinks, focusing on properties essential for successful tissue engineering and creating functional organ structures.

Keywords:
3D printingBioinkBiomaterialsRegenerative medicineTissue engineering

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Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Materials Science

Background:

  • Increasing global demand for organ replacement and tissue regeneration.
  • Tissue engineering and 3D bioprinting offer solutions for damaged organs.
  • Bioinks are critical components for developing functional 3D-printed tissues and organs.

Purpose of the Study:

  • To review the state-of-the-art in polymer-based bioinks for 3D printing.
  • To outline essential requirements for selecting effective bioinks.
  • To discuss the combination of cells, polymers, and biosignals in bioink formulations.

Main Methods:

  • Review of recent literature on polymer-based bioinks for 3D bioprinting.
  • Analysis of bioink properties: biocompatibility, printability, and mechanical stability.
  • Discussion of bioink formulations including cells, biomaterials, and biosignals.

Main Results:

  • Various bioink formulations exist, from cell-biomaterial composites to cell aggregates.
  • Functional polymeric biomaterials enable tunable bioinks.
  • Blending cells and hydrogels enhances bioink properties.

Conclusions:

  • Emerging bioinks offer improved biocompatibility, printability, and mechanical stability.
  • These advancements hold significant potential for creating complex tissue and organ structures.
  • Future applications of 3D bioprinting in regenerative medicine are promising.