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Second-site prosthetic joint infection in patients with multiple prosthetic joints

Kevin Clesham1, Andrew J Hughes2, Sven O' hEireamhoin2

  • 1Department of Trauma and Orthopaedic Surgery, Galway University Hospitals, Newcastle Road, Galway, Ireland. kevinclesham@gmail.com.

European Journal of Orthopaedic Surgery & Traumatology : Orthopedie Traumatologie
|April 12, 2018
PubMed
Abstract

Insights

Patients with multiple prosthetic joints are at higher risk for second prosthetic joint infections (PJIs), particularly those with total knee replacements or MRSA carrier status. Early identification of these patients is crucial to reduce infection risks.

Area of Science:

  • Orthopedic surgery
  • Infectious diseases
  • Epidemiology

Background:

  • Prosthetic joint infections (PJIs) are severe complications following arthroplasty.
  • Multiple prosthetic joints increase patient morbidity and the likelihood of revision procedures.
  • Understanding risk factors for second-site PJIs in patients with multiple prostheses is critical.

Purpose of the Study:

  • To investigate the incidence and risk factors for second-site PJIs in patients with multiple prosthetic joints.
  • To identify patient characteristics associated with recurrent or new prosthetic joint infections.

Main Methods:

  • Retrospective review of an institutional arthroplasty database (2004-2017).
  • Inclusion of patients with more than one prosthetic joint and a PJI diagnosis.
  • Data collection included risk factors, causative organisms, procedure counts, and length of stay.

Main Results:

  • Four out of 44 patients (9.1%) developed a second-site PJI.
  • Eight patients (18.2%) experienced re-infection of the primary PJI site.
  • Positive MRSA carrier status and PJI of a total knee replacement were linked to increased risk of subsequent infection.

Conclusions:

  • Patients with multiple prostheses and subsequent infections exhibit higher morbidity and resource utilization.
  • Total knee replacement PJIs and MRSA carrier status are significant risk factors for secondary infections.
  • Early identification of high-risk patients is essential for implementing preventative strategies against further PJIs.
Keywords:
ArthroplastyComplicationInfectionProsthetic jointRevision surgery

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