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Related Concept Videos

Blood Pressure01:24

Blood Pressure

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The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
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Blood Pressure01:30

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Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
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Measurement of Blood Pressure01:17

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Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
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Factors affecting Blood pressure01:28

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Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
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Alterations in Blood Pressure01:30

Alterations in Blood Pressure

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Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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Related Experiment Video

Updated: Feb 12, 2026

Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke
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Blood Pressure Goals in Acute Stroke-How Low Do You Go?

Iryna Lobanova1, Adnan I Qureshi2

  • 1Zeenat Qureshi Stroke Institute, St. Cloud, MN, USA. lobanovanmu@gmail.com.

Current Hypertension Reports
|April 12, 2018
PubMed
Summary

Aggressively lowering blood pressure (BP) is not recommended for acute ischemic stroke due to neutral clinical outcomes. However, immediate BP reduction targeting systolic BP to 140 mmHg is recommended for acute intracerebral hemorrhages.

Keywords:
Blood pressureIntracerebral hemorrhageIschemic stroke

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Area of Science:

  • Neurology
  • Cardiology
  • Emergency Medicine

Background:

  • Elevated systolic blood pressure (BP) > 140 mmHg is common in acute ischemic stroke (75%) and intracerebral hemorrhage (ICH) (80%).
  • Managing hypertension in acute stroke patients is critical for patient outcomes.

Purpose of the Study:

  • To summarize and update current knowledge on managing elevated BP in acute stroke patients.
  • To differentiate management strategies for ischemic stroke versus ICH.

Main Methods:

  • Review of recent clinical trials and current guidelines.
  • Analysis of evidence for BP reduction effects on stroke outcomes.

Main Results:

  • BP reduction shows neutral effects on clinical outcomes in acute ischemic stroke.
  • Guidelines recommend BP < 180/105 mmHg for ischemic stroke patients receiving intravenous thrombolysis, but optimal post-reperfusion BP is unclear.
  • Randomized trials support immediate BP lowering to target systolic BP of 140 mmHg in acute ICH.

Conclusions:

  • Aggressive BP reduction is not recommended for acute ischemic stroke due to lack of supporting evidence.
  • Current guidelines recommend targeting systolic BP to 140 mmHg for acute intracerebral hemorrhage management.