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Updated: Feb 12, 2026

A Novel Model of Mild Traumatic Brain Injury for Juvenile Rats
Published on: December 8, 2014
Characterization of children hospitalized with traumatic brain injuries after building falls
Kirsten V Loftus1, Tara Rhine2, Shari L Wade3
1Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Kirsten.Loftus@cchmc.org.
Insights
Children who fall from buildings and sustain traumatic brain injuries (TBI) have more severe outcomes. Non-urban children with building fall TBI are at higher risk for serious head injuries, necessitating targeted prevention.
Area of Science:
- Pediatric Traumatology
- Public Health
- Epidemiology
Background:
- Unintentional falls are a leading cause of pediatric traumatic brain injury (TBI).
- Building falls represent a high-risk mechanism for severe pediatric TBI, morbidity, and mortality.
- Limited data exists on the characteristics of children hospitalized with building fall-related TBI.
Purpose of the Study:
- To characterize children hospitalized with TBI from building falls.
- To compare building fall TBI cases with TBI cases from other fall mechanisms.
- To assess the impact of urban versus non-urban residence on TBI severity in building fall incidents.
Main Methods:
- Secondary analysis of the Pediatric Health Information System (PHIS) administrative database (2009-2014).
- Inclusion of children under 15 years old with TBI-related diagnoses due to falls (ICD9-CM codes).
- Calculation of Injury Severity Score (ISS) and head Abbreviated Injury Scale (AIS) scores; dichotomization of head AIS into minor/moderate and serious/severe.
Main Results:
- The cohort included 23,813 children; 933 (3.9%) experienced building falls.
- Building fall TBI cases showed a higher proportion of serious/severe TBI (63.4%) compared to other falls (53.9%, p < 0.01).
- Among building fall TBI cases, non-urban children had a higher likelihood of serious/severe TBI (58.9%) versus urban children (53.6%, p < 0.01).
Conclusions:
- Children hospitalized with TBI from building falls experience more severe injuries than those from other fall types.
- While most building fall TBI cases are from urban areas, non-urban children are disproportionately affected by serious head injuries.
- Prevention strategies for building fall-related TBI should be expanded to include non-urban populations.
Background:
Unintentional falls cause a substantial proportion of pediatric traumatic brain injury (TBI), with building falls carrying particularly high risk for morbidity and mortality. The cohort of children sustaining building fall-related TBI has not been well-examined. We sought to characterize children hospitalized with building fall-related TBIs and evaluate if specific factors distinguished these children from children hospitalized with TBI due to other fall mechanisms. We secondarily assessed if TBI severity among children injured due to a building fall varied between children from urban versus non-urban areas.
Methods:
This was a secondary analysis of the Pediatric Health Information System (PHIS), an administrative database from pediatric hospitals. We identified children < 15 years old, hospitalized between 2009 and 2014, with an associated TBI-related diagnosis due to a fall as determined by International Classification of Diseases, Clinical Modification, Ninth revision (ICD9-CM) diagnosis codes. Urban versus non-urban status was determined using PHIS-assigned Rural-Urban Commuting Area codes. Injury severity (i.e. Injury Severity Score (ISS) and head Abbreviated Injury Scale (AIS) score) were calculated. Head AIS scores were dichotomized into minor/moderate (1-2) and serious/severe (3-6) for analysis. Frequencies, descriptive statistics, Chi-square analysis, and Mann-Whitney U analysis characterized populations and determined group differences.
Results:
The study cohort included 23,813 children, of whom 933 (3.9%) fell from buildings. Within the building fall cohort, 707 (75.8%) resided in urban areas, 619 (66.3%) were male, 513 (55.0%) were white, and 528 (56.6%) had government insurance; the mean age was 3.8 years (SD 2.9). There was a larger proportion of children with serious/severe TBI among those injured from building falls relative to other falls (63.4% vs 53.9%, p < 0.01). Among children injured from building falls, those from non-urban areas were more likely to sustain a serious/severe TBI relative to urban children (58.9% vs 53.6%, p < 0.01).
Conclusions:
Children hospitalized following buildings falls with TBI sustained more severe injuries relative to other fall types. Although a majority of children hospitalized with building fall related-TBIs were from urban areas, those from non-urban areas frequently sustained serious head injuries. Future research should target expanding prevention efforts to include non-urban areas.
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