Related Experiment Video
Updated: Feb 12, 2026
08:04
Measuring Sensitivity to Viewpoint Change with and without Stereoscopic Cues
Published on: December 4, 2013
4.8K
Why kidneys fail post-partum: a tubulocentric viewpoint.
Patricia Villie1, Marc Dommergues2, Isabelle Brocheriou3,4
1APHP, Hôpital Tenon, Urgences Néphrologiques et Transplantation Rénale, 4 rue de la Chine, 75020, Paris, France.
Journal of Nephrology
|April 12, 2018
Summary
Postpartum kidney injury can occur due to various complications. This review highlights the critical role of renal tubular damage in pregnancy-related acute kidney injury (AKI) and its management.
Area of Science:
- Nephrology
- Obstetrics
- Critical Care Medicine
Background:
- Pregnancy and postpartum periods present unique risks for kidney function.
- Conditions like preeclampsia and hemorrhage can severely impact renal health.
- Renal tubular epithelium is particularly vulnerable during this time.
Purpose of the Study:
- To review kidney disease in pregnancy and postpartum.
- To focus on tubular damage in pregnancy-related acute kidney injury (AKI).
- To aid clinical reasoning for postpartum AKI.
Main Methods:
- Non-systematic literature review.
- Inclusion of clinical experience.
- Analysis based on recent Kidney Disease/Improving Global Outcome (KDIGO) guidelines.
Main Results:
- Pregnancy-related conditions threaten endothelium and renal tubular epithelium.
- AKI following delivery can be rapid and irreversible.
- Underestimated importance of tubular epithelium in the peripartum period.
Conclusions:
- Understanding renal tissue characteristics around delivery is crucial.
- Defining pregnancy-related AKI using KDIGO guidelines is essential.
- Urinalysis, imaging, and biopsy aid in diagnosing postpartum AKI.
Related Concept Videos
01:17Hypothesis: Accept or Fail to Reject?
29.6K
The outcome of any hypothesis testing leads to rejecting or not rejecting the null hypothesis. This decision is taken based on the analysis of the data, an appropriate test statistic, an appropriate confidence level, the critical values, and P-values. However, when the evidence suggests that the null hypothesis cannot be rejected, is it right to say, 'Accept' the null hypothesis?
There are two ways to indicate that the null hypothesis is not rejected. 'Accept' the null...
There are two ways to indicate that the null hypothesis is not rejected. 'Accept' the null...
29.6K
01:45Kidney Structure
75.5K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
75.5K
01:28Kidney Transplant I: Introduction
498
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
498
01:21External Anatomy of the Kidney
3.9K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
3.9K
01:12Internal Anatomy of the Kidney
7.0K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
7.0K
01:27Post-traumatic Stress Disorder
590
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
590