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Cannabis for Chronic Pain: Challenges and Considerations
E Alfonso Romero-Sandoval1, Jack E Fincham2, Ashley L Kolano2
1Department of Anesthesiology, Pain Mechanisms Laboratory, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Pharmacotherapy
|April 12, 2018
Summary
Cannabis plant shows effectiveness for chronic pain relief, while cannabinoids offer moderate improvement for sleep disturbances. This review examines the scientific evidence and challenges surrounding cannabis in pain management.
Area of Science:
- Medical research
- Pharmacology
- Pain management
Background:
- National Academies report indicates cannabis plant efficacy for adult chronic pain.
- Cannabinoids show moderate evidence for improving sleep disturbances in chronic pain patients.
- Legalization of cannabis presents challenges due to overlap of recreational and medicinal use.
Purpose of the Study:
- Analyze scientific evidence on cannabis for chronic pain.
- Address controversial questions regarding cannabis in healthcare.
- Facilitate discussion on cannabis' role in pain management.
Main Methods:
- Review of scientific literature on cannabis and pain.
- Analysis of evidence for cannabis plant vs. cannabinoid molecules.
- Examination of legal and clinical challenges.
Main Results:
- Substantial evidence supports cannabis plant for chronic pain.
- Moderate evidence suggests cannabinoids improve sleep disturbances.
- Recreational cannabis availability poses risks to patients.
Conclusions:
- Cannabis' paradoxical efficacy challenges current medical paradigms.
- Legal status and responsible use are critical considerations.
- Further discussion needed on integrating cannabis into pain management.
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