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Clinico-epidemiological Study of Morphea from a Tertiary Care Hospital
Tasleem Arif1, Mohammad Adil1, Syed S Amin1
1Department of Dermatology, STDs and Leprosy, Jawaharlal Nehru Medical College (JNMC), Aligarh Muslim University (AMU), Aligarh, India.
Introduction:
Morphea is an uncommon disease that presents with skin induration and sclerosis. The disease is common in Caucasians and there are few studies describing the clinicoepidemiological profile of these patients from the Indian subcontinent.
Methods:
This prospective study was conducted during a three year period from June 2014 to May 2017. All patients of morphea presenting to the dermatology outpatient department were evaluated for parameters like age, sex, duration, age of onset, clinical subtype and possible disease associations and triggering factors. The data was analysed, tabulated and mean, standard deviation and percentages calculated.
Results:
47 patients were incorporated into the study. These comprised of 10 (21.28%) males and 37 (78.72%) females. The average age of the patients was 23.92 ± 12.07 years with a mean age of onset being 22.13 ± 12.51 years. 22 (46.80%) patients presented within one year of onset of disease. Plaque morphea was the commonest type seen in 31 (65.96%) patients followed by linear morphea in 9 (19.15%) patients. We found preceding trauma in 3 patients and morphea developed following herpes zoster and intramuscular injection in one patient each.
Conclusion:
Morphea is an uncommon disease that is seen predominantly in females and young individuals. Circumscribed plaque morphea is the commonest variant. Certain predisposing factors like trauma can precede it.
Insights
Morphea, a rare skin condition causing induration and sclerosis, predominantly affects young females. Plaque morphea is the most common subtype, with trauma sometimes preceding its onset.
Area of Science:
- Dermatology
- Epidemiology
Background:
- Morphea is an uncommon condition characterized by skin induration and sclerosis.
- Limited clinicoepidemiological data exists for morphea patients in the Indian subcontinent.
Purpose of the Study:
- To describe the clinicoepidemiological profile of morphea patients.
- To identify common clinical subtypes and potential triggering factors.
Main Methods:
- Prospective study conducted over three years (June 2014 - May 2017).
- Evaluation of 47 morphea patients for age, sex, onset, subtype, and associations.
- Data analysis included calculating means, standard deviations, and percentages.
Main Results:
- The study included 47 patients: 37 (78.72%) females and 10 (21.28%) males.
- Average age was 23.92 ± 12.07 years; mean age of onset was 22.13 ± 12.51 years.
- Plaque morphea (65.96%) was most common, followed by linear morphea (19.15%). Trauma preceded onset in 3 patients.
Conclusions:
- Morphea predominantly affects young females and is most commonly the plaque subtype.
- Predisposing factors such as trauma may precede the development of morphea.
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