Upper respiratory tract infection in mouse and rats
1Life Science Research Israel, Ness-Ziona.
Mycopathologia
|February 1, 1988
Abstract:
Spontaneous aspergilloma in the para-nasal cavities of 2 rats, and a chronic granuloma with grains, caused by Gram-positive cocci in the maxillary sinus of a mouse, are reported.
Insights
Spontaneous fungal infections, aspergilloma, were found in rat nasal cavities. Additionally, a bacterial granuloma was observed in a mouse
Area of Science:
- Veterinary Pathology
- Mycology
- Bacteriology
Background:
- Spontaneous infections in laboratory animals can impact research.
- Para-nasal and sinus cavities are susceptible to various pathogens.
Observation:
- Two cases of spontaneous aspergilloma were identified in the para-nasal cavities of rats.
- A chronic granuloma, containing bacterial grains from Gram-positive cocci, was found in the maxillary sinus of a mouse.
Findings:
- Aspergilloma, a fungal infection, occurred spontaneously in rat nasal passages.
- Bacterial infection led to chronic granuloma formation in a mouse's maxillary sinus.
Implications:
- Highlights the importance of monitoring for spontaneous infections in rodent models.
- These findings contribute to understanding differential diagnoses in rodent sinonasal pathology.
