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Related Experiment Videos

[Current contact allergens].

P J Frosch1

  • 1Universitäts-Hautklinik Heidelberg.

Zeitschrift Fur Hautkrankheiten
|December 1, 1987
PubMed
Summary
This summary is machine-generated.

Patch testing revealed that 25.9% of 2,623 dermatology patients had positive reactions to allergens. Nickel sulfate, balsam of Peru, and formaldehyde were the most common culprits, highlighting key triggers for allergic contact dermatitis.

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Area of Science:

  • Dermatology
  • Allergology
  • Contact Dermatitis

Context:

  • Presents patch test results from 2,623 patients treated at the University of Heidelberg's Department of Dermatology between July 1984 and June 1986.
  • Evaluates the prevalence and patterns of positive reactions to a broad range of allergens.

Purpose:

  • To identify the most frequent allergens causing positive patch test reactions in a large patient cohort.
  • To analyze the distribution of positive reactions among tested allergens and identify specific high-prevalence triggers.

Summary:

  • A significant proportion (25.9%) of patients exhibited at least one positive patch test reaction.
  • 257 allergens elicited 1,450 positive reactions, with a small subset of allergens (9.7%) responsible for a majority (64.4%) of reactions.

Related Experiment Videos

  • The most common allergens identified were nickel sulfate, balsam of Peru, formaldehyde, neomycin sulfate, and cobalt sulfate.

    • Impact:

    • Provides crucial data on common contact allergens, aiding dermatologists in diagnosing and managing allergic contact dermatitis.
    • Highlights the significance of specific allergens like nickel sulfate and formaldehyde, informing public health initiatives and product formulation.
    • Identifies occupational allergens such as glyceril monothioglycolate in hairdressers, underscoring the need for targeted prevention strategies.