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Updated: Aug 13, 2026
Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System
Published on: September 20, 2018
A retrospective study of 91 cases with gastroschisis or omphalocele 1956-1985
Insights
Treatment for infant abdominal wall defects has improved, but mortality remains high for complex cases like omphalocele and gastroschisis. Implants are recommended for large omphalocele defects when primary closure isn't feasible.
Area of Science:
- Pediatric Surgery
- Neonatal Care
- Congenital Malformations
Background:
- Abdominal wall defects, including gastroschisis and omphalocele, are serious congenital conditions in infants.
- Treatment outcomes for these defects have evolved over the past three decades.
Purpose of the Study:
- To review the treatment experiences of 91 infants with abdominal wall defects over 30 years.
- To analyze trends and outcomes, particularly the increasing incidence of gastroschisis in the last decade.
- To evaluate treatment strategies for large omphalocele defects and associated complications.
Main Methods:
- Retrospective review of 91 infant cases with abdominal wall defects treated over 30 years.
- Analysis of treatment outcomes, mortality rates, and complication frequencies.
- Specific focus on 36 patients treated in the last 10 years, detailing their clinical course.
Main Results:
- Overall treatment results have significantly improved during the study period.
- A notable increase in gastroschisis occurrence was observed in the last 10 years.
- High mortality rates persist for omphalocele with multiple malformations and gastroschisis with intestinal atresia.
- Implants are suggested for large omphalocele defects unsuitable for primary closure, over silastic silos or skin flaps.
Conclusions:
- While treatment for infant abdominal wall defects has advanced, complex cases present ongoing challenges.
- Early identification and appropriate management, including the use of implants for large omphaloceles, are crucial.
- Further research into optimizing outcomes for high-risk infants is warranted.
Abstract:
The experiences of treatment of 91 infants with abdominal wall defects during thirty years are presented. The occurrence of gastroschisis increased during the last ten years. The results of treatment have improved markedly during the period of study but there is still a high mortality rate in children with omphalocele and multiple concomitant malformations and in children with gastroschisis and coexisting intestinal atresia. In cases with large omphalocele defects, if primary closure is not possible, an implant is recommended instead of silastic silo, skin flap closure or mercurochrome application. The clinical course in thirty-six patients during the last ten years is reported.
