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Hydroa vacciniforme-like cutaneous T-cell lymphoma in a child: A case report
Jingyi Li1, Yiheng Zan, Hongjie Liu
1Department of Pediatrics, West China Second University Hospital Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education Department of Dermatology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Rationale:
Hydroa vacciniforme (HV)-like T-cell lymphoma is a rare malignancy in childhood associated with Epstein-Barr virus infection.
Patient Concerns:
A 6-year old girl presented with complaint of 3-year history of recurrent skin lesions, 3 months of fever accompanied by cough for 8 days.
Diagnoses:
Skin biopsy revealed a HV-like lymphoma presentation and positive signals of EBER were detected by in situ hybridization. TCR-γ gene monoclonal rearrangement was present. A HV-like cutaneous T-cell lymphoma was diagnosed.
Interventions:
The girl was treated with cyclosporine and CHOP.
Outcomes:
The girl's condition had been stable for 6 months.
Lessons:
Our case highlights the necessity for taking the HV-like lymphoma as a differential diagnosis especially when a patient manifests as recurrent skin lesions accompanied by systemic involvement.
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