Related Experiment Video
Updated: Feb 12, 2026

Isolation and Transplantation of Hematopoietic Stem Cells HSCs
Published on: February 25, 2007
Hematopoietic stem cell transplantation in its 60s: A platform for cellular therapies
Christian Chabannon1, Jurgen Kuball2, Attilio Bondanza3
1Institut Paoli-Calmettes, Centre de Lutte Contre le Cancer, Université d'Aix-Marseille, INSERM CBT 1409, Centre d'Investigations Cliniques en Biothérapie, F-13009 Marseille, France. bonini.chiara@hsr.it chabannonc@ipc.unicancer.fr.
Abstract:
Over the last 60 years, more than a million patients received hematopoietic cell transplantation. Having incorporated multiple changes in clinical practices, it remains a complex procedure facing a dual challenge: cure of the underlying disease and prevention of relapse while controlling potentially severe complications. Improved understanding of underlying biological processes resulted in the design of innovative therapies engineered from defined cell populations and testing of these therapies as addition or substitution at virtually every step of the procedure. This review provides an overview of these developments, many of them now applied outside the historical field of hematopoietic cell transplantation.
Related Concept Videos
Multipotency of Hematopoietic Stem Cells
Regulation of Hematopoietic Stem Cells
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Induced Pluripotent Stem Cells
Gene Therapy
Adult Stem Cells

