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Related Concept Videos

Chirality02:25

Chirality

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Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
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Chirality in Nature02:30

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Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
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Screw: Problem Solving01:21

Screw: Problem Solving

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In mechanical engineering, the interaction between a threaded screw shaft and a plate gear involves analyzing the resisting torque on the plate gear that can be overpowered when a specific torsional moment is applied to the shaft. To better comprehend this concept, consider a generic situation with a threaded screw shaft with a given mean radius and lead and a plate gear with a specified mean radius. The coefficient of static friction between the screw and gear is also provided.
To evaluate the...
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Self-Locking Screw01:16

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A square-threaded screw jack is a mechanical device widely used for lifting heavy loads or applying considerable force. One of the key features that can make a screw jack more effective and reliable is its self-locking capability.
A square-threaded screw jack carrying a load is considered self-locking if the screw retains its position even after the moment applied to it is removed.
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Ionic Crystal Structures02:42

Ionic Crystal Structures

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Ionic crystals consist of two or more different kinds of ions that usually have different sizes. The packing of these ions into a crystal structure is more complex than the packing of metal atoms that are the same size.
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Frictional Forces on Screws01:17

Frictional Forces on Screws

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Screws are characterized by a helical ridge known as a thread wrapped around a cylindrical shaft. They are commonly used as fasteners to hold objects together or to transmit power and motion in machines. One type of screw that is particularly useful for transmitting power is the square-threaded screw.
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Related Experiment Video

Updated: Feb 12, 2026

A Micropatterning Assay for Measuring Cell Chirality
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A Micropatterning Assay for Measuring Cell Chirality

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Chirality-controlled crystallization via screw dislocations.

Baeckkyoung Sung1, Alexis de la Cotte1, Eric Grelet2

  • 1Centre de Recherche Paul-Pascal, CNRS & Université de Bordeaux, 115 Avenue Schweitzer, 33600, Pessac, France.

Nature Communications
|April 13, 2018
PubMed
Summary
This summary is machine-generated.

Topological defects like screw dislocations can amplify chirality from small particles to large helical structures during crystallization. This discovery offers new ways to control chiral material properties.

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Theoretical Calculation and Experimental Verification for Dislocation Reduction in Germanium Epitaxial Layers with Semicylindrical Voids on Silicon
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Theoretical Calculation and Experimental Verification for Dislocation Reduction in Germanium Epitaxial Layers with Semicylindrical Voids on Silicon
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Author Spotlight: High-Throughput Screening to Obtain Crystal Hits for Protein Crystallography
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Area of Science:

  • Chemistry
  • Nanotechnology
  • Materials Science

Background:

  • Chirality is crucial in various scientific fields, including chemistry and nanotechnology.
  • Understanding chirality amplification from building blocks to superstructures is challenging.

Purpose of the Study:

  • To investigate how chirality is transferred and amplified from chiral particles to supramolecular structures during crystallization.
  • To explore the role of topological defects in this chirality amplification process.

Main Methods:

  • Utilized a model system of chiral particles for direct imaging during crystal growth.
  • Analyzed the crystallization kinetic pathway and the influence of screw dislocations.
  • Investigated the interplay of geometrical frustration, thermal fluctuations, and particle chirality.

Main Results:

  • Demonstrated that screw dislocations drive chirality transfer from the particle to the supramolecular level.
  • Showed that crystallization kinetics and defects control chirality amplification, leading to homohelical structures from racemic mixtures.
  • Provided a mechanistic explanation involving geometrical frustration, racemization, and particle chirality.

Conclusions:

  • Screw dislocations are key to promoting crystal growth and controlling chiral morphology.
  • This mechanism allows for the amplification of chirality in crystalline states, influencing their functionality.
  • The findings offer insights into designing and controlling chiral materials.