Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Milgram's Obedience to Authority

Milgram's Obedience to Authority

Obedience to authority is classically demonstrated in a more famous series of social psychology experiments performed by Stanley Milgram. He was a social psychology professor at Yale who was influenced by the trial of Adolf Eichmann, a Nazi war criminal. Eichmann’s defense for the atrocities he committed was that he was “just following orders.”

CRISPR

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...

CRISPR and crRNAs

CRISPR and crRNAs

Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...

Distance Corrections

Distance Corrections

To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...

Power Factor Correction

Power Factor Correction

The power transmission to a factory involves the transfer of apparent power, a combination of active and reactive power. The power factor measures how effectively electrical power is converted into useful work output. The ratio of the real power (KW) that does the work to the apparent power (KVA) supplied to the circuit.

NMR Spectrometers: Resolution and Error Correction

NMR Spectrometers: Resolution and Error Correction

When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

"Alkaline-Hammer Strategy" Breaks Acidic and Stromal Barriers to Induce Alkaliptosis and Enhance Immunotherapy in Pancreatic Cancer.

Angewandte Chemie (International ed. in English)·2026

Same author

Cardiac regeneration and repair: the emerging mechanisms and therapeutic approaches.

Molecular biomedicine·2026

Same author

Medical image local augmentation via text- and mask-guided diffusion model.

Medical physics·2026

Same author

Hypoxia-induced upregulation of lncRNA SLC9A3-AS1 promotes lung adenocarcinoma progression through the miR-506-5p/ASPH/NOTCH1 pathway.

Scientific reports·2026

Same author

CDK10 loss primes tumor cells for transcriptional vulnerability and sensitizes to CDK12/13 inhibition.

Cell death & disease·2026

Same author

Structural basis of Fumosorinone-mediated allosteric inhibition of PTP1B for cancer immunotherapy.

Communications biology·2026

Search research articles

Related Experiment Video

Updated: Feb 12, 2026

A Universal Protocol for Large-scale gRNA Library Production from any DNA Source

A Universal Protocol for Large-scale gRNA Library Production from any DNA Source

Published on: December 6, 2017

Author Correction: Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries.

Swee Hoe Ong¹, Yilong Li¹, Hiroko Koike-Yusa¹

¹Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.

Scientific Reports

|April 13, 2018

Summary

This study has a correction notice. The error mentioned in the article has not yet been fixed in the paper.

More Related Videos

Pooled CRISPR-Based Genetic Screens in Mammalian Cells

Pooled CRISPR-Based Genetic Screens in Mammalian Cells

Published on: September 4, 2019

A Customizable Protocol for String Assembly gRNA Cloning STAgR

A Customizable Protocol for String Assembly gRNA Cloning STAgR

Published on: December 26, 2018

Related Experiment Videos

Last Updated: Feb 12, 2026

A Universal Protocol for Large-scale gRNA Library Production from any DNA Source

A Universal Protocol for Large-scale gRNA Library Production from any DNA Source

Published on: December 6, 2017

Pooled CRISPR-Based Genetic Screens in Mammalian Cells

Pooled CRISPR-Based Genetic Screens in Mammalian Cells

Published on: September 4, 2019

A Customizable Protocol for String Assembly gRNA Cloning STAgR

A Customizable Protocol for String Assembly gRNA Cloning STAgR

Published on: December 26, 2018

Area of Science:

Scientific publishing
Article errata

Context:

A correction notice has been issued for this article.
The identified error persists in the published version.

Purpose:

To inform readers about an uncorrected error in the article.
To ensure transparency in scientific communication.

Summary:

A published article contains an error.
A correction notice is available, but the original paper remains unamended.

Impact:

Readers should be aware of the uncorrected error.
This highlights the importance of rigorous proofreading in scientific publications.