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[Contact allergy to dexpanthenol].

W Keilig1

  • 1Dermatologischen und Allergologischen Abteilung, Städtischen Krankenhauses München-Schwabing.

Dermatosen in Beruf Und Umwelt. Occupation and Environment
|November 1, 1987
PubMed
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Dexpanthenol, a common ingredient in ointments, can cause allergic contact dermatitis. Allergy testing confirmed this in a patient with leg ulcers, highlighting dexpanthenol as a potential allergen.

Area of Science:

  • Dermatology
  • Allergology
  • Contact Dermatitis

Background:

  • Postthrombotic leg ulcers and stasis dermatitis are chronic conditions often treated with topical ointments.
  • Contact dermatitis is a common adverse reaction to topical medications.

Observation:

  • A 56-year-old female patient with a leg ulcer experienced a reaction to a dexpanthenol-containing ointment.
  • This reaction was consistent with contact dermatitis, a condition previously linked to dexpanthenol in 1965.

Findings:

  • Recent allergy testing confirmed the patient's sensitivity to dexpanthenol.
  • Positive reactions were observed for pure dexpanthenol and two associated additives.

Implications:

  • Dexpanthenol should be recognized as a potential contact allergen.

Related Experiment Videos

  • Clinicians should consider dexpanthenol allergy in patients with unexplained dermatitis, especially those using relevant topical products.