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Updated: Feb 12, 2026

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
Unilateral Brown Fat Suppression on FDG PET/CT-detecting Sympathetic Denervation
Saurabh Arora1, Nishikant Avinash Damle1, K Sreenivasa Reddy1
1Department of Nuclear Medicine, AIIMS, New Delhi, India.
Abstract:
We present here a case of primitive neuroectodermal tumor (PNET) who initially presented with involvement of the right 3rd rib and underwent neoadjuvant chemotherapy, rib excision, and adjuvant chemoradiotherapy and later underwent posterolateral thoracotomy, pleural nodule excision, and the right 11th rib metastatic lesion excision. Follow-up 18F-FDG PET/CT/computed tomography revealed unilateral brown fat suppression in the form of decreased metabolic uptake in the ipsilateral cervical, axillary, and paravertebral brown fat as compared to metabolically active contralateral brown fat, likely due to paravertebral sympathetic chain damage.
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