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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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The evaluation of left ventricular diastolic dysfunction in patients with non-hemorrhagic stroke and atrial

Mahdi Najafi-Dalui1, Hasan Shemirani2, Reyhaneh Zavar3

  • 1Resident, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

ARYA Atherosclerosis
|April 13, 2018
PubMed

Insights

Left ventricular diastolic dysfunction (LVDD) is not linked to the CHA2DS2-VASc score in patients experiencing non-hemorrhagic stroke and atrial fibrillation (AF). This finding suggests LVDD may not be a primary predictor in this patient group.

Area of Science:

  • Cardiology
  • Neurology
  • Internal Medicine

Background:

  • Atrial fibrillation (AF) is a common arrhythmia and a significant risk factor for stroke.
  • The CHA2DS2-VASc score assesses embolic event risk and guides anticoagulant therapy.
  • Left ventricular diastolic dysfunction (LVDD) is a potential complication in cardiovascular disease.

Purpose of the Study:

  • To investigate the relationship between LVDD and the CHA2DS2-VASc score.
  • To evaluate LVDD in patients with non-hemorrhagic stroke and concurrent AF.

Main Methods:

  • Cross-sectional study of 76 patients with suspected non-hemorrhagic stroke and AF.
  • Collected demographic, anthropometric, and clinical data.
  • Calculated CHA2DS2-VASc scores and performed transthoracic echocardiograms to assess LVDD.

Main Results:

  • The mean age of patients was 64.64 years; 36.8% were women.
  • Hypertension was the most common comorbidity (65.8%).
  • LVDD was present in 21.1% of patients and was not statistically associated with the CHA2DS2-VASc score (r = 0.151, P = 0.192).

Conclusions:

  • LVDD is not associated with the CHA2DS2-VASc score in patients with non-hemorrhagic stroke and AF.
  • This suggests that LVDD may not be a significant factor in predicting stroke risk based on the CHA2DS2-VASc score in this population.
Abstract

Keywords:
Atrial FibrillationLeft Ventricular DysfunctionStroke

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