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Updated: Feb 12, 2026

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

Cicatricial alopecia.

Varvara Kanti¹, Joachim Röwert-Huber¹, Annika Vogt¹

¹Department of Dermatology, Venereology, and Allergology, Charité - University Medical Center, Berlin, Germany.

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

|April 13, 2018

Summary

This summary is machine-generated.

Primary cicatricial alopecias (PCA) involve various inflammatory patterns, often leading to delayed diagnosis and irreversible hair loss. Treatment focuses on halting progression and managing inflammation, not regrowth in scarred areas.

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Area of Science:

Dermatology
Trichology
Pathology

Background:

Primary cicatricial alopecias (PCA) are classified by inflammatory infiltrate patterns.
Early diagnosis is challenging due to subclinical onset and slow progression.
Limited evidence exists for PCA treatment efficacy.

Purpose of the Study:

To outline diagnostic approaches for primary cicatricial alopecias.
To review current therapeutic strategies for managing PCA.
To emphasize the goals of PCA treatment: halting hair loss and scarring.

Main Methods:

Detailed patient history and dermatological examination, including trichoscopy.
Biopsy for clinically unclear cases.
Review of anti-inflammatory, antimicrobial, and immunomodulatory therapies.

Main Results:

Diagnosis can be difficult in early or late stages, necessitating biopsy.
Topical or intralesional corticosteroids are often considered.
Systemic therapy choice depends on the inflammatory infiltrate type.

Conclusions:

Treatment aims to stop or slow hair loss and scarring, reduce inflammation, and alleviate symptoms.
Hair regrowth in scarred areas is not expected.
Psychological support and camouflage are important adjuncts for patients.