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Epidemiology, risk factors and characteristics of pediatric stroke: a nationwide population-based study
K-L Chiang1,2,3, C-Y Cheng3,4
1From the Department of Pediatrics, Kuang-Tien General Hospital, No. 117, Shatian Road Shalu District, Taichung City 43302.
Insights
Pediatric stroke, a significant cause of childhood death and disability, is more common in infants, boys, and lower socioeconomic groups. Hemorrhagic stroke carries a higher mortality rate than ischemic stroke.
Area of Science:
- Pediatric Neurology
- Epidemiology
- Public Health
Background:
- Stroke is a leading cause of death and chronic morbidity in children.
- Characterized as an acute acquired neurological deficit, pediatric stroke requires further epidemiological investigation.
Purpose of the Study:
- To determine the period prevalence, incidence, and risk factors of pediatric stroke in Taiwan.
- To analyze mortality rates and identify associated risk factors.
Main Methods:
- Utilized the National Health Insurance Research Database for Taiwan inhabitants aged 1 month to 18 years (2010-2011).
- Collected data on age, sex, location, and household income.
- Evaluated incidence, period prevalence, mortality rates, and potential risk factors.
Main Results:
- Hemorrhagic stroke exhibited a significantly higher mortality rate (27.6%) compared to ischemic stroke (10.2%).
- Underlying diseases or risk factors were identified in 77.8% of pediatric stroke patients.
- Common risk factors included vascular diseases (26.3%), infections (14.0%), and cardiac disorders (9.1%).
Conclusions:
- Infants under 2 years, boys, and children from lower socioeconomic backgrounds face a higher risk of stroke.
- Hemorrhagic stroke has a significantly higher mortality rate than ischemic stroke.
- Over half of pediatric stroke cases had underlying conditions, with distinct causes for hemorrhagic versus ischemic stroke.
Background:
Stroke, classically characterized as an acute acquired neurological deficit, is an important leading cause of death and chronic morbidity in children.
Aims:
This study reported the period prevalence, incidence and risk factors of pediatric stroke in Taiwan.
Methods And Procedures:
All Taiwan inhabitants aged 1 month to 18 years registered in the National Health Insurance Research Database between 2010 and 2011 were enrolled in this study. Factors including age, sex, location and household income levels were collected. Incidence, period prevalence, mortality rate and the possible risks were completely evaluated. Outcomes and results: Hemorrhagic stroke has a significantly higher mortality rate than ischemic stroke (27.6% vs. 10.2%, P<0.05). Risk factors or underlying diseases for stroke were identified in 77.8% of the patients and 16.2% had more than one risk factor. The most common risk factors were vascular diseases (26.3%), infection (14.0%) and cardiac disorders (9.1%).
Conclusions And Implications:
Infants younger than 2 years, boys and children in lower socioeconomic status have a significantly higher risk of stroke. Hemorrhagic stroke has a significantly higher mortality rate than ischemic stroke. More than half of the children with stroke had underlying diseases and the causes of hemorrhagic stroke are significantly different from ischemic stroke.
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