Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

2.1K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
2.1K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.7K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.7K
Adult Stem Cells01:33

Adult Stem Cells

33.9K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
33.9K
Plant Cells and Tissues02:01

Plant Cells and Tissues

65.9K
Plant tissues are collections of similar cells performing related functions. Different plant tissues will have their own specialized roles and can be combined with other tissues to form organs such as flowers, fruit, stem, and leaves. Two major types of plant tissue include meristematic and permanent tissue.
65.9K
Embryonic Stem Cells00:58

Embryonic Stem Cells

32.6K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
32.6K
Embryonic Stem Cells00:57

Embryonic Stem Cells

5.2K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
5.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Control of synaptic communication through molecularly engineered bioluminescence light emission and sensing.

Communications biology·2026
Same author

Proteomics reveal PTEN as a critical mediator of sustained mitochondrial dysfunction during chronic spinal cord injury.

Experimental neurology·2026
Same author

A bioluminescent activity dependent platform, BLADe, for converting intracellular activity to photoreceptor activation.

Scientific reports·2026
Same author

Magneto-Photonic Gene Circuit for Minimally Invasive Control of Gene Expression in Mammalian Cells.

ACS omega·2026
Same author

Magneto-Photonic Gene Circuit for Minimally Invasive Control of Gene Expression in Mammalian Cells.

bioRxiv : the preprint server for biology·2025
Same author

CaBLAM: a high-contrast bioluminescent Ca<sup>2+</sup> indicator derived from an engineered Oplophorus gracilirostris luciferase.

Nature methods·2025

Related Experiment Video

Updated: Feb 12, 2026

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues
09:20

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues

Published on: March 31, 2016

30.1K

Neural Stem Cells Derived Directly from Adipose Tissue.

Eric D Petersen1, Jessica R Zenchak1, Olivia V Lossia1

  • 1Program in Neuroscience, Central Michigan University , College of Medicine, Mount Pleasant, Michigan.

Stem Cells and Development
|April 13, 2018
PubMed
Summary

Researchers have developed a new method to derive neural stem cells (NSCs) from adipose tissue. These adult stem cells can differentiate into functional neurons, offering a promising alternative for treating neurological disorders.

Keywords:
cell culturegrowth factorsneurospheresstem cell transplantation

More Related Videos

Isolation, Culture, and Adipogenic Induction of Neural Crest Original Adipose-Derived Stem Cells from Periaortic Adipose Tissue
08:31

Isolation, Culture, and Adipogenic Induction of Neural Crest Original Adipose-Derived Stem Cells from Periaortic Adipose Tissue

Published on: March 2, 2020

6.5K
Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats
10:50

Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats

Published on: April 7, 2023

4.2K

Related Experiment Videos

Last Updated: Feb 12, 2026

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues
09:20

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues

Published on: March 31, 2016

30.1K
Isolation, Culture, and Adipogenic Induction of Neural Crest Original Adipose-Derived Stem Cells from Periaortic Adipose Tissue
08:31

Isolation, Culture, and Adipogenic Induction of Neural Crest Original Adipose-Derived Stem Cells from Periaortic Adipose Tissue

Published on: March 2, 2020

6.5K
Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats
10:50

Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats

Published on: April 7, 2023

4.2K

Area of Science:

  • Neuroscience
  • Stem Cell Biology
  • Regenerative Medicine

Background:

  • Neural stem cells (NSCs) are crucial for central nervous system development and repair.
  • Embryonic NSCs are effective but raise ethical and feasibility concerns for human therapies.
  • Adult stem cells offer a practical alternative, with some exhibiting neural potential.

Purpose of the Study:

  • To establish a direct method for deriving neural stem cells from adipose tissue.
  • To evaluate the potential of adipose-derived NSCs for neuronal differentiation and function.
  • To provide an ethically viable and feasible source of NSCs for therapeutic applications.

Main Methods:

  • Collection and in vitro culture of cells from adipose tissue.
  • Direct isolation of NSCs without intermediate cell types (e.g., mesenchymal stem cells).
  • Assessment of NSC phenotype, expansion capabilities, and differentiation into neuronal cells.

Main Results:

  • A novel method successfully isolated and cultured adipose-derived neural stem cells.
  • These cells demonstrated in vitro expansion and differentiation into functional neurons.
  • Adipose-derived neurons exhibited spontaneous electrical activity and network characteristics similar to embryonic-derived neurons.

Conclusions:

  • Adipose tissue is a viable source for generating neural stem cells.
  • Adipose-derived NSCs possess a similar phenotype and functional potential to embryonic NSCs.
  • This method offers a promising, ethically sound approach for neural stem cell-based therapies.