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Published on: December 15, 2010
Hyaluronic acid-based biopharmaceutical delivery and tumor-targeted drug delivery system
Gangliang Huang1, Hualiang Huang2
1Active Carbohydrate Research Institute, Chongqing Normal University, Chongqing, 401331, China.
Abstract:
Hyaluronic acid (HA) is a natural polysaccharide with good biocompatibility and degradability. HA and its derivatives can be used as sustained-release carriers for drugs, which can delay the release of drugs and have a long-acting effect. They can be used for the delivery of various drugs such as proteins, nucleic acids and anti-tumor drugs. HA and its derivatives can specifically bind to multiple receptors on the cell surface and can be used for targeted drug delivery, especially for the delivery of anti-tumor drugs. Thus, there are different forms of tumor-targeted drug delivery systems based on HA.
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