Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Reconstruction of Signal using Interpolation01:10

Reconstruction of Signal using Interpolation

741
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
741
Primary Active Transport01:47

Primary Active Transport

200.7K
In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps that are embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction...
200.7K
Primary Active Transport01:29

Primary Active Transport

14.5K
In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction they would...
14.5K
Primary and Secondary Growth in Roots and Shoots03:02

Primary and Secondary Growth in Roots and Shoots

60.7K
Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
60.7K
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.9K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.9K
Primary Production01:06

Primary Production

25.5K
The total amount of energy acquired by primary producers in an ecosystem is called gross primary production (GPP). However, of this energy, producers use some for metabolic processes, and some is lost as heat, decreasing the amount of energy available to the next trophic level. The remaining usable amount of energy is called the net primary productivity (NPP). In terrestrial ecosystems, NPP is driven by climate, while light penetration and nutrient availability drive NPP in aquatic ecosystems.
25.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multicenter multinational retrospective study of the 1-year natural history of LI-RADS 3 observations in patients with cirrhosis.

European radiology·2026
Same author

Diagnostic Performance of PSMA PET/MRI in Characterizing LI-RADS 3 Observations in Patients with Cirrhosis.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025
Same author

Per-Lesion Assessment of Individual MRI Sequences and 68 Ga-DOTATATE PET in Neuroendocrine Liver Metastases.

Investigative radiology·2025
Same author

Prognostic value of MRI-derived features for biochemical recurrence after curative radiotherapy in prostate cancer.

Abdominal radiology (New York)·2025
Same author

<sup>68</sup>Ga-DOTATATE PET/CT versus MRI in neuroendocrine liver metastases: a comprehensive per-lesion analysis.

La Radiologia medica·2025
Same author

MRI-derived quantification of hepatic vessel-to-volume ratios in chronic liver disease using a deep learning approach.

European radiology experimental·2025

Related Experiment Video

Updated: Feb 12, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
08:01

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

9.5K

Fistulectomy with primary sphincter reconstruction.

Steffen Seyfried1, Dieter Bussen2, Andreas Joos2

  • 1Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. steffen.seyfried@umm.de.

International Journal of Colorectal Disease
|April 14, 2018
PubMed
Summary

Fistulectomy with primary sphincter reconstruction offers a high healing rate for high anal fistulas, significantly reducing recurrence compared to other methods. This sphincter-saving approach is a viable option for complex cases.

Keywords:
Anal fistulaContinenceFistulectomyPrimary reconstructionRecurrenceSeton

More Related Videos

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

7.1K
Three-Dimensional Reconstruction of Orbital Fractures
08:18

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

715

Related Experiment Videos

Last Updated: Feb 12, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
08:01

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

9.5K
A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

7.1K
Three-Dimensional Reconstruction of Orbital Fractures
08:18

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

715

Area of Science:

  • Colorectal Surgery
  • Surgical Innovation
  • Anal Fistula Treatment

Background:

  • High anal fistulas present a surgical challenge with high recurrence rates and potential for continence disorders.
  • Traditional fistulectomy has high rates of incontinence, while sphincter-saving procedures and seton treatments have limitations.
  • Advancements in direct repair for distal fistulas have paved the way for improved techniques in proximal fistula management.

Purpose of the Study:

  • To evaluate the efficacy of fistulectomy with primary sphincter reconstruction for high anal fistulas.
  • To assess the healing rates and recurrence of this surgical technique.
  • To analyze the impact on patient continence and overall outcomes.

Main Methods:

  • Retrospective evaluation of patients undergoing fistulectomy with primary sphincter reconstruction at a University Medical Center.
  • Prospective database analysis from June 2003 to November 2015.
  • Inclusion of all patients who underwent the specified surgical procedure.

Main Results:

  • A primary healing rate of 88.2% was achieved, increasing to 95.8% with secondary repairs.
  • Factors like gender and fistula location significantly influenced outcomes.
  • Post-operative incontinence was observed in 23.0% of patients, primarily flatus incontinence.

Conclusions:

  • Fistulectomy with primary sphincter reconstruction is a feasible and effective procedure for high anal fistulas.
  • This technique demonstrates a low recurrence rate, outperforming other methods for transsphincteric fistulas.
  • Continence disorders associated with this procedure appear to be of minor clinical significance for patients.