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[Respiratory hypercapnic-hypoxic training is an effective component of complex therapy of polyneuropathy in children

K V Smirnov1, Yu V Smirnova1, V P Kulikov2

  • 1Altai Regional Children's Clinical Hospital, Barnaul, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|April 14, 2018
PubMed

Insights

Respiratory hypercapnic-hypoxic training improved neuropathy in children with type 1 diabetes. This therapy enhanced nerve function and reduced neurological deficits, offering a significant clinical benefit.

Area of Science:

  • Endocrinology
  • Neurology
  • Respiratory Medicine

Background:

  • Diabetic polyneuropathy is a common complication of type 1 diabetes.
  • Effective therapeutic strategies are needed to manage diabetic neuropathy.

Purpose of the Study:

  • To evaluate the effectiveness of respiratory hypercapnic-hypoxic training as part of complex therapy for type 1 diabetes-related neuropathy.

Main Methods:

  • Fifty children with type 1 diabetes and polyneuropathy were enrolled.
  • Patients were divided into a main group (receiving standard therapy plus respiratory training) and a comparison group (standard therapy only).
  • Clinical and neurophysiological assessments, including electromyography (EMG), were performed.

Main Results:

  • Both groups showed positive clinical and neurophysiological changes.
  • The main group, undergoing respiratory training, demonstrated more significant improvements.
  • Key improvements included reduced fasting glucose, decreased neurological deficit scores (NIS-LL), and enhanced nerve conduction velocity.

Conclusions:

  • Respiratory hypercapnic-hypoxic training is a valuable addition to the pathogenetic therapy for diabetes mellitus and its associated polyneuropathy.
  • The training yields significant clinical effects, improving glycemic control and neurological outcomes.
Abstract

Keywords:
childrendiabeteshypercapnic hypoxiapolyneuropathy

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