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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Value-Based ST-Segment-Elevation Myocardial Infarction Care Using Risk-Guided Triage and Early Discharge
Joseph E Ebinger1, Craig E Strauss1, Ross R Garberich1
1Cedars-Sinai Smidt Heart Institute at Cedars-Sinai Medical Center, Los Angeles, CA (J.E.E., T.D.H.). Minneapolis Heart Institute at Abbott Northwestern Hospital, MN (C.E.S., S.M.B., P.R., I.J.C., A.K.P., T.D.H.). Minneapolis Heart Institute Foundation, MN (R.R.G., S.M.B., B.R.P.).
Implementing a ST-segment-elevation myocardial infarction (STEMI) risk score enables early discharge for low-risk patients, reducing costs without compromising care quality. This risk-guided approach improves healthcare value for STEMI treatment.
Area of Science:
- Cardiology
- Health Economics
- Clinical Triage
Background:
- Prior studies suggest early discharge for low-risk ST-segment-elevation myocardial infarction (STEMI) patients post-primary percutaneous coronary intervention.
- The study addresses the need to decrease healthcare costs associated with STEMI care while maintaining optimal patient outcomes.
Purpose of the Study:
- To implement and evaluate an STEMI risk score for guiding patient triage and discharge.
- To assess the impact of risk-guided care on healthcare value, including costs and patient outcomes.
Main Methods:
- Retrospective application of the Zwolle Risk Score to 967 patients undergoing primary percutaneous coronary intervention (2009-2011).
- Development and electronic medical record integration of a modified Zwolle Risk Calculator for a fast-track protocol.
- Prospective evaluation of the protocol in 549 STEMI patients.
Main Results:
- Low-risk STEMI patients (62% prospectively) had significantly lower complication rates (8.3% vs 38.7%) and in-hospital mortality (0.4% vs 12.5%) compared to high-risk patients.
- The fast-track protocol for low-risk patients resulted in a shorter median length of stay (2 days vs 3 days) and lower overall costs ($6720 vs $11,783).
- On-protocol low-risk patients demonstrated further reductions in length of stay and costs compared to off-protocol patients and those in the retrospective cohort.
Conclusions:
- Risk-guided triage and early discharge for STEMI patients after primary percutaneous coronary intervention enhance healthcare value.
- The implemented protocol successfully reduced costs without negatively impacting patient outcomes or quality of care.
- The modified Zwolle Risk Calculator effectively supports the fast-track protocol for eligible low-risk STEMI patients.
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