Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Failed lumbar disk syndrome.

F Guarnera1, P Mancuso, G Augello

  • 1Neurosurgical Institute, University of Catania.

Zentralblatt Fur Neurochirurgie
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Under 2$ hand anesthesia? Our first 800 cases with Wide-Awake Local Anesthesia No Tourniquet (WALANT) in hand surgery.

Musculoskeletal surgery·2024
Same author

Alcohol-related Liver Disease and sepsis.

European review for medical and pharmacological sciences·2021
Same author

Correction to: Gr-MDSC-linked asset as a potential immune biomarker in pretreated NSCLC receiving nivolumab as second-line therapy.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2019
Same author

Gr-MDSC-linked asset as a potential immune biomarker in pretreated NSCLC receiving nivolumab as second-line therapy.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2019
Same author

Urban blue: A global analysis of the factors shaping people's perceptions of the marine environment and ecological engineering in harbours.

The Science of the total environment·2019
Same author

The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.

Leukemia·2017
Same journal

Prof. Dr. med. habil. Georg Merrem (1908-1971)--a historical vignette.

Zentralblatt fur Neurochirurgie·2008
Same journal

Dorsal corporectomy in a Ewing sarcoma situated in the pedicle of the L5 vertebral body.

Zentralblatt fur Neurochirurgie·2008
Same journal

Tumor growth of suspected meningiomas in clinically healthy 80-year-olds: a follow up five years later.

Zentralblatt fur Neurochirurgie·2008
Same journal

Quantitative assessment of postoperative blood collection in brain tumor surgery under valproate medication.

Zentralblatt fur Neurochirurgie·2008
Same journal

Meningioma 40 years after radiation therapy for retinoblastoma: genetic and phenotypic analysis, and minireview of literature.

Zentralblatt fur Neurochirurgie·2008
Same journal

Hemorrhage into cystic vestibular schwannoma following stereotactic radiation therapy.

Zentralblatt fur Neurochirurgie·2008
See all related articles

Failed Lumbar Disk Syndrome (FLDS) affects 8 of 210 patients after surgery. Pain may stem from neural pathway abnormalities, and prevention is key due to poor treatment outcomes for this condition.

Area of Science:

  • Neurosurgery
  • Pain Management
  • Spinal Surgery

Background:

  • Failed Lumbar Disk Syndrome (FLDS) is a challenging complication following lumbar disk surgery.
  • Understanding the underlying pathophysiology of FLDS pain is crucial for effective management.
  • Current therapeutic options for iatrogenic deafferentation pain in FLDS show limited efficacy.

Purpose of the Study:

  • To report cases of FLDS and discuss associated risk factors.
  • To explore the neurobiological basis of pain in FLDS patients.
  • To emphasize the importance of preventative strategies for FLDS.

Main Methods:

  • Retrospective analysis of 8 FLDS cases among 210 patients who underwent slipped disk surgery.
  • Review of literature concerning risk factors and pain mechanisms in FLDS.

Related Experiment Videos

  • Discussion of neuroanatomical structures implicated in FLDS pain, including substantia gelatinosa and Lissauer's tract.

    • Main Results:

    • Identified 8 cases of FLDS in a cohort of 210 operated patients.
    • Discussed potential risk factors contributing to the development of FLDS.
    • Hypothesized that abnormalities in the substantia gelatinosa or Lissauer's tract neurons may cause FLDS pain.

    Conclusions:

    • FLDS is a significant concern after lumbar disk surgery, with a notable incidence.
    • Pain in FLDS may be linked to specific neural pathway dysfunctions.
    • Preventative measures are paramount due to the poor response of iatrogenic deafferentation pain to existing therapies.