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Updated: Feb 11, 2026

Transcranial Direct Current Stimulation tDCS in Mice
Published on: September 23, 2018
Frontotemporal stimulation modulates semantically-guided visual search during confrontation naming: A combined tDCS
Richard J Binney1, Sameer A Ashaie2, Bonnie M Zuckerman3
1School of Psychology, Bangor University, Gwynedd, Wales, UK; Department of Communication Sciences and Disorders, Temple University, Philadelphia, PA, USA.
Abstract:
Transcranial direct current stimulation (tDCS) was paired with eye tracking to elucidate contributions of frontal, temporoparietal and anterior temporal cortex to early visual search patterns during picture naming (e.g., rapid visual scanning to diagnostic semantic features). Neurotypical adults named line drawings of objects prior to and following tDCS in three separate sessions, each employing a unique electrode montage. The gaze data revealed montage by stimulation (pre/post) interaction effects characterized by longer initial visual fixations (mean difference = 89 ms; Cohen's d = .8) and cumulative fixation durations (mean difference = 98 ms; Cohen's d = .9) on key semantic features (e.g., the head of an animal) after cathodal frontotemporal stimulation relative to the pre-stimulation baseline. We interpret these findings as reflecting a tDCS-induced modulation of semantic contributions of the anterior temporal lobe(s) to top-down influences on object recognition. Further, we discuss implications for the optimization of tDCS for the treatment of anomia in aphasia.
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