The Risk of Adverse Events Related to Extended-Dwell Peripheral Intravenous Access

Sara Campagna1, Silvia Gonella2, Pietro Antonio Zerla3

  • 11Department of Public Health and Pediatric Sciences,University of Torino,via Santena 5 bis,10126 Torino,Italy.

Insights

Midline catheters (MCs) offer a safe alternative to repeated venipuncture for prolonged IV infusions. Analysis of two Italian hospital databases revealed a low rate of MC-related adverse events, suggesting their utility in patient care.

Area of Science:

  • Medical Devices
  • Infection Control
  • Patient Safety

Background:

  • Midline catheters (MCs) are increasingly used for extended intravenous (IV) therapy.
  • They aim to reduce complications associated with frequent venipuncture.
  • Assessing the safety profile of MCs is crucial for clinical practice.

Purpose of the Study:

  • To evaluate the safety and incidence of adverse events (AEs) associated with midline catheter use in a real-world hospital setting.
  • To determine the rate of MC-related AEs per 1,000 catheter days.

Main Methods:

  • Retrospective analysis of data from two Italian hospital databases.
  • Inclusion of 1,538 adult patients who received midline catheters.
  • Systematic recording and categorization of all MC-related adverse events.

Main Results:

  • A total of 154 MC-related adverse events were reported among 1,538 patients.
  • This represents an incidence of 10% of patients experiencing at least one AE.
  • The overall rate of AEs was 2.49 per 1,000 MC days.

Conclusions:

  • Midline catheters demonstrate a favorable safety profile for patients requiring prolonged intravenous infusions.
  • The incidence of adverse events is relatively low, supporting their use as a viable alternative to repeated venipuncture.
  • Further research can optimize MC utilization and minimize potential complications.

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