Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Base Excision Repair01:54

Base Excision Repair

26.4K
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
26.4K
Detection of Gross Error: The Q Test01:00

Detection of Gross Error: The Q Test

7.1K
When one or more data points appear far from the rest of the data, there is a need to determine whether they are outliers and whether they should be eliminated from the data set to ensure an accurate representation of the measured value. In many cases, outliers arise from gross errors (or human errors) and do not accurately reflect the underlying phenomenon. In some cases, however, these apparent outliers reflect true phenomenological differences. In these cases, we can use statistical methods...
7.1K
Lewis Acids and Bases02:33

Lewis Acids and Bases

48.5K
In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
48.5K
Weak Base Solutions03:21

Weak Base Solutions

25.4K
Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...
25.4K
Ions as Acids and Bases02:54

Ions as Acids and Bases

26.6K
Salts with Acidic Ions
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
26.6K
DNA Base Pairing02:27

DNA Base Pairing

33.7K
Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
33.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uniform zinc oxide nanowire arrays grown on nonepitaxial surface with general orientation control.

Nano letters·2013
Same author

[American head and neck surgery progress of in 2012].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2013
Same author

A compact thermo-optical multimode-interference silicon-based 1 × 4 nano-photonic switch.

Optics express·2013
Same author

Experimental demonstration of 110-Gb/s unsynchronized band-multiplexed superchannel coherent optical OFDM/OQAM system.

Optics express·2013
Same author

Potentially functional variants of p14ARF are associated with HPV-positive oropharyngeal cancer patients and survival after definitive chemoradiotherapy.

Carcinogenesis·2013
Same author

Enhanced molecular transport in hierarchical silicalite-1.

Langmuir : the ACS journal of surfaces and colloids·2013
Same journal

Smartphone-assisted fluorescence and colorimetric dual-mode sensor for visual quantitative detection of nitrite and nitrate in real samples.

Analytica chimica acta·2026
Same journal

Folding integrated all-paper photoelectrochemical immunoassay using annealed ZnO for point-of-care detection of ferritin.

Analytica chimica acta·2026
Same journal

Dual-mode electrochemical-SERS detection of chloramphenicol based on dual-signal enhancement.

Analytica chimica acta·2026
Same journal

Multi-screening of beta-lactam antibiotics in milk based on Fe<sub>3</sub>O<sub>4</sub>@phage/bacteria system and aggregation induced emission luminogen.

Analytica chimica acta·2026
Same journal

A porous phosphate-rich β-cyclodextrin polymer for efficient and broad-spectrum enrichment of antibiotics.

Analytica chimica acta·2026
Same journal

Corrigendum to "LUMIN: A novel algorithm for automated mixture quantification using 1D <sup>1</sup>H NMR spectra" [Analytica Chimica Acta 1411 (2026) 345639].

Analytica chimica acta·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
14:04

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

25.2K

Aptamer-based microcantilever-array biosensor for profenofos detection.

Chao Li1, Guangping Zhang1, Shangquan Wu1

  • 1CAS Key Laboratory of Mechanical Behavior and Design of Material, Department of Modern Mechanics, University of Science and Technology of China, Hefei, 230027, China.

Analytica Chimica Acta
|April 16, 2018
PubMed
Summary
This summary is machine-generated.

A new aptamer-based microcantilever sensor offers highly sensitive, label-free detection of the pesticide profenofos. This advancement holds significant potential for ensuring food security by enabling rapid, real-time monitoring of harmful residues.

Keywords:
AptamerLabel-freeMicrocantilever sensorProfenofosSurface stress

More Related Videos

Detecting Anastasis In Vivo by CaspaseTracker Biosensor
20:16

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

9.8K
An Aptamer-based Sensor for Unchelated GadoliniumIII
05:15

An Aptamer-based Sensor for Unchelated GadoliniumIII

Published on: January 9, 2017

7.8K

Related Experiment Videos

Last Updated: Feb 11, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
14:04

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

25.2K
Detecting Anastasis In Vivo by CaspaseTracker Biosensor
20:16

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

9.8K
An Aptamer-based Sensor for Unchelated GadoliniumIII
05:15

An Aptamer-based Sensor for Unchelated GadoliniumIII

Published on: January 9, 2017

7.8K

Area of Science:

  • Analytical Chemistry
  • Biosensors
  • Nanotechnology

Background:

  • Organophosphorus pesticides like profenofos pose risks to food security and human health.
  • Existing detection methods for profenofos often lack the required sensitivity or speed.
  • There is a critical need for advanced analytical techniques for sensitive and rapid pesticide residue detection.

Purpose of the Study:

  • To develop a novel aptamer-based microcantilever-array sensor for the sensitive and label-free detection of profenofos.
  • To evaluate the sensor's performance in terms of sensitivity, selectivity, and real-time detection capabilities.
  • To assess the potential of the sensor for practical applications in food safety monitoring.

Main Methods:

  • Functionalization of microcantilevers with a specific aptamer (SS2-55) for profenofos recognition.
  • Operation of the microcantilever-array sensor in stress mode to detect binding events.
  • Real-time monitoring of microcantilever deflection via an optical method upon profenofos interaction.
  • Validation of sensor selectivity using a different organophosphorus pesticide and testing with real samples (vegetable-soak solution).

Main Results:

  • The aptamer-functionalized microcantilever sensor demonstrated label-free, quantitative, and real-time detection of profenofos.
  • A low detection limit of 1.3 ng/mL (3.5 nM) was achieved, surpassing other aptamer-based methods.
  • The sensor exhibited high selectivity and successfully detected profenofos in a vegetable-soak solution.
  • Microcantilever deflection correlated positively with increasing profenofos concentrations.

Conclusions:

  • The developed aptamer-based microcantilever-array sensor is a highly sensitive and convenient tool for detecting profenofos.
  • This label-free sensing approach offers significant potential for improving food security through effective residue monitoring.
  • The sensor's real-time and quantitative capabilities make it suitable for rapid analysis in food safety applications.