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The efficient workflow to decrease the manual microscopic examination of urine sediment using on-screen review of

Eun-Jung Cho1, Dae-Hyun Ko2, Woochang Lee2

  • 1Department of Laboratory Medicine, The Catholic University of Korea, Uijeongbu St. Mary's Hospital, Seoul, Republic of Korea.

Clinical Biochemistry
|April 16, 2018
PubMed
Summary
This summary is machine-generated.

Automated urinalysis systems like Cobas 6500 significantly reduce manual microscopic examination (MME) of urine sediment compared to UF-1000i. Combining analyzers further decreases MME rates, improving efficiency in clinical diagnostics.

Keywords:
Automated urinalysisImage analysisMicroscopyUrine sediment

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Area of Science:

  • Clinical Chemistry
  • Laboratory Medicine
  • Diagnostic Technology

Background:

  • Manual microscopic examination (MME) of urine sediment is inefficient and imprecise.
  • Automated urinalysis systems offer potential improvements over MME.
  • This study evaluates two automated systems for urine sediment analysis.

Purpose of the Study:

  • To assess the rate of MME using UF-1000i and Cobas 6500 automated analyzers.
  • To compare the performance of each analyzer individually and in combination.
  • To determine the impact of automated systems on reducing manual workload.

Main Methods:

  • Analysis of 1055 in-patient and 1119 out-patient urine specimens.
  • Utilized UF-1000i (Sysmex) and Cobas 6500 (Roche) automated urine sediment analyzers.
  • Evaluated MME rates with individual and combined analyzer use.

Main Results:

  • Cobas 6500 alone reduced MME rates to 15.6% (in-patients) and 3.7% (out-patients), versus 34.2% and 16.8% for UF-1000i.
  • Combined UF-1000i then Cobas 6500: 11.3% MME for in-patients, 2.7% for out-patients.
  • Combined Cobas 6500 then UF-1000i: 11.3% MME for in-patients, 2.7% for out-patients.

Conclusions:

  • Cobas 6500 significantly decreases MME rates compared to UF-1000i for both in- and out-patients.
  • Combined use of analyzers further reduces MME and on-screen review rates.
  • Automated systems enhance efficiency in urine sediment analysis.