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[Alcohol withdrawal syndrome dynamics during treatment with nooclerin (deanoli aceglumas)]
T V Agibalova1, O Zh Buzik2, O V Rychkova3
1Research Center for Substance Use Disorders, Moscow, Russia; Russian University for Friendship, Moscow, Russia.
Aim:
To study the efficacy of nooclerin (deanoli aceglumas) in alcohol withdrawal syndrome assessed by clinical and biochemical characteristics.
Material And Methods:
A multicenter, open, randomized, comparative study of nooclerin in the complex treatment of alcohol withdrawal syndrome included 90 patients. The patients were randomized into nooclerin group (n=55) and control group (n=35).
Results And Conclusion:
Nooclerin reduced alcohol withdrawal symptoms more significantly throughout the whole study period. There were significant between-group differences on the Clinical Institute Withdrawal Assessment of Alcohol Scale (CIWA-Ar) and the Multidimensional Fatigue Inventory (МFI-20). However, patients exhibited no excessive activity. No adverse side-effects were observed.
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