Related Experiment Video
Updated: Feb 11, 2026
02:30
Endoscopic Approach for Colloid Cyst Resection
Published on: May 23, 2025
829
Current status and future perspectives of endoscopic full-thickness resection
Hirohito Mori1, Hideki Kobara1, Noriko Nishiyama1
1Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Summary
Endoscopic full-thickness resection (EFTR) is an advanced technique for removing digestive tract tumors. While effective for gastrointestinal stromal tumors, complications like perforation can occur, necessitating further development.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Oncology
Background:
- Flexible endoscopy has evolved from diagnostic biopsy to therapeutic resection of neoplasms.
- Endoscopic full-thickness resection (EFTR) is an emerging advanced endoscopic technique.
- Conventional exposed EFTR has shown promise but requires further evaluation.
Purpose of the Study:
- To systematically review conventional exposed EFTR procedures.
- To evaluate indications, outcomes, and complications of EFTR.
- To discuss advancements in EFTR techniques and devices.
Main Methods:
- Systematic review of studies on conventional exposed EFTR.
- Searched literature from 2015-2017 using keywords: EFTR, over-the-scope clip (OTSC), Overstitch System.
- Included four retrospective, single-center studies.
Main Results:
- Gastrointestinal stromal tumors are a suitable indication for EFTR (mean size 20.71 mm).
- Endoclips for closure were complication-free in two studies; OTSC use was associated with delayed perforation in others.
- Procedure times ranged from 40 to 105 minutes.
Conclusions:
- Conventional exposed EFTR is feasible, particularly for gastrointestinal stromal tumors.
- Complication rates, including delayed perforation, highlight the need for improved closure techniques.
- Emerging techniques like non-exposed EFTR and new suturing devices show future potential.
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