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Updated: Feb 11, 2026

Experimental Model of Ligature-Induced Peri-Implantitis in Mice
Published on: May 17, 2024
Clinical characteristics of peri-implant mucositis and peri-implantitis
Ausra Ramanauskaite1,2, Kathrin Becker3, Frank Schwarz4
1Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
Objectives:
To evaluate and correlate clinical parameters associated with peri-implant diseases based on established case definitions.
Materials And Methods:
A total of 75 patients exhibiting 269 implants (healthy: 77; peri-implant mucositis: 77; peri-implantitis: 115) were included in this observational study. Clinical parameters included bleeding on probing (BOP), probing depths (PDs), and suppuration (Supp).
Results:
Healthy sites were associated with the absence of BOP, while mean BOP in peri-implant mucositis and peri-implantitis patients amounted to 20.83% and 71.33%, corresponding to 43% and 86% at the implant level (p < .001), respectively. Peri-implantitis patients exhibited significantly higher mean PD values (4.46 mm) when compared with the peri-implant mucositis group (2.70 mm, p < .001). Supp was limited to peri-implantitis cases and detected in 30.16% of the patients (implant level: 17.39%). The regression model revealed a significant linear association between the number of BOP-positive sites around the implant (minimum 0, maximum 6) and mean PD values at peri-implant mucositis and peri-implantitis sites at both patient and implant levels.
Conclusions:
The clinical parameters investigated were shown to be associated with the severity of peri-implant diseases.
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