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Anaemia and red blood cell transfusion in intracranial neurosurgery: a comprehensive review

A Kisilevsky1, A W Gelb2, M Bustillo3

  • 1Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver General Hospital, Vancouver, BC, Canada.

British Journal of Anaesthesia
|April 18, 2018
PubMed

Both anaemia and blood transfusion are associated with poor outcomes in the neurosurgical population. Based on the available literature, the optimal haemoglobin concentration for neurologically injured patients appears to be in the range of 9.0-10.0 g dl-1, although the individual risks and benefits should be weighed. Several perioperative blood conservation strategies have been used successfully in neurosurgery, including correction of anaemia and coagulopathy, use of antifibrinolytics, and intraoperative cell salvage. Avoidance of non-steroidal anti-inflammatory drugs and starch-containing solutions is recommended given the potential for platelet dysfunction.

Keywords:
anaemiacoagulationneurosurgerytransfusion

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